Metabolomics and malaria biology
V Lakshmanan, KY Rhee, JP Daily - Molecular and biochemical …, 2011 - Elsevier
Metabolomics has ushered in a novel and multi-disciplinary realm in biological research. It
has provided researchers with a platform to combine powerful biochemical, statistical …
has provided researchers with a platform to combine powerful biochemical, statistical …
Plasmodium immunomics
DL Doolan - International journal for parasitology, 2011 - Elsevier
The Plasmodium parasite, the causative agent of malaria, is an excellent model for
immunomic-based approaches to vaccine development. The Plasmodium parasite has a …
immunomic-based approaches to vaccine development. The Plasmodium parasite has a …
New antigens for a multicomponent blood-stage malaria vaccine
An effective blood-stage vaccine against Plasmodium falciparum remains a research
priority, but the number of antigens that have been translated into multicomponent vaccines …
priority, but the number of antigens that have been translated into multicomponent vaccines …
[HTML][HTML] A full-length recombinant Plasmodium falciparum PfRH5 protein induces inhibitory antibodies that are effective across common PfRH5 genetic variants
LY Bustamante, SJ Bartholdson, C Crosnier… - Vaccine, 2013 - Elsevier
The lack of an effective licensed vaccine remains one of the most significant gaps in the
portfolio of tools being developed to eliminate Plasmodium falciparum malaria. Vaccines …
portfolio of tools being developed to eliminate Plasmodium falciparum malaria. Vaccines …
A library of functional recombinant cell-surface and secreted P. falciparum merozoite proteins
C Crosnier, M Wanaguru, B McDade, FH Osier… - Molecular & Cellular …, 2013 - ASBMB
Malaria, an infectious disease caused by parasites of the Plasmodium genus, is one of the
world's major public health concerns causing up to a million deaths annually, mostly …
world's major public health concerns causing up to a million deaths annually, mostly …
RH5–Basigin interaction plays a major role in the host tropism of Plasmodium falciparum
M Wanaguru, W Liu, BH Hahn… - Proceedings of the …, 2013 - National Acad Sciences
Plasmodium falciparum, the cause of almost all human malaria mortality, is a member of the
Laverania subgenus which infects African great apes. Interestingly, Laverania parasites …
Laverania subgenus which infects African great apes. Interestingly, Laverania parasites …
Plasmodium Kinases As Targets For New-Generation Antimalarials
There is an urgent need for the development of new antimalarial drugs with novel modes of
actions. The malarial parasite, Plasmodium falciparum, has a relatively small kinome of< …
actions. The malarial parasite, Plasmodium falciparum, has a relatively small kinome of< …
Histidine affinity tags affect MSP142 structural stability and immunodominance in mice
Inclusion of affinity tags has greatly facilitated process development for protein antigens,
primarily for their recovery from complex mixtures. Although generally viewed as supportive …
primarily for their recovery from complex mixtures. Although generally viewed as supportive …
Vaccine candidate discovery for the next generation of malaria vaccines
J Tuju, G Kamuyu, LM Murungi, FHA Osier - Immunology, 2017 - Wiley Online Library
Although epidemiological observations, IgG passive transfer studies and experimental
infections in humans all support the feasibility of developing highly effective malaria …
infections in humans all support the feasibility of developing highly effective malaria …
Preliminary characterization of Plasmodium vivax sporozoite antigens as pre-erythrocytic vaccine candidates
J Nicholas, SL De, P Thawornpan… - PLoS Neglected …, 2023 - journals.plos.org
Plasmodium vivax pre-erythrocytic (PE) vaccine research has lagged far behind efforts to
develop Plasmodium falciparum vaccines. There is a critical gap in our knowledge of PE …
develop Plasmodium falciparum vaccines. There is a critical gap in our knowledge of PE …