[HTML][HTML] Genetic and environmental factors associated with type 2 diabetes and diabetic vascular complications

M Murea, L Ma, BI Freedman - The review of diabetic studies: RDS, 2012 - ncbi.nlm.nih.gov
Faced with a global epidemic of type 2 diabetes (T2D), it is critical that researchers improve
our understanding of the pathogenesis of T2D and related vascular complications. These …

[HTML][HTML] Reactive metabolites and antioxidant gene polymorphisms in type 2 diabetes mellitus

M Banerjee, P Vats - Redox biology, 2014 - Elsevier
Type 2 diabetes mellitus (T2DM), by definition is a heterogeneous, multifactorial, polygenic
syndrome which results from insulin receptor dysfunction. It is an outcome of oxidative stress …

Glutathione S‐transferase genes and the risk of type 2 diabetes mellitus: Role of sexual dimorphism, gene–gene and gene–smoking interactions in disease …

I Azarova, O Bushueva, A Konoplya… - Journal of …, 2018 - Wiley Online Library
摘要背景目前认为在2 型糖尿病的发病机制中缺乏对活性氧(reactive oxygen species, ROS)
的防御作用非常重要; 因此, 编码抗氧化防御酶基因可能会影响疾病的易感性 …

Candidate gene studies of diabetic retinopathy in human

P Priščáková, G Minárik, V Repiská - Molecular biology reports, 2016 - Springer
Diabetic retinopathy (DR) is a multifactorial disease with complex pathophysiology. It is the
main cause of blindness among the people in productive age. The purpose of this literature …

Update on genetics and diabetic retinopathy

BM Hampton, SG Schwartz, MA Brantley Jr… - Clinical …, 2015 - Taylor & Francis
Clinical risk factors for diabetic retinopathy (DR), such as duration of disease and degree of
glucose control, do not adequately predict disease progression in individual patients …

Association of polymorphisms in antioxidant enzyme-encoding genes with diabetic nephropathy in a group of Saudi arabian patients with type II diabetes mellitus

FI Albeladi, MM Mostafa, MA Zayed… - International journal of …, 2022 - Taylor & Francis
Introduction An imbalance between reactive oxygen species (ROS) generation and the
defence mechanisms underlying the activity of antioxidant enzymes has been demonstrated …

Influence of GSTM1, GSTT1, and GSTP1 Polymorphisms on Type 2 Diabetes Mellitus and Diabetic Sensorimotor Peripheral Neuropathy Risk

A Stoian, C Bănescu, RI Bălaşa, A Moţăţăianu… - Disease …, 2015 - Wiley Online Library
Background and Aims. Diabetic neuropathy is a frequent complication of type 2 diabetes
mellitus (T2DM). Genetic susceptibility and oxidative stress may play a role in the …

Oxidative stress genes, antioxidants and coronary artery disease in type 2 diabetes mellitus

M Tibaut, D PetroviĦ# 141 - Cardiovascular & Hematological …, 2016 - benthamdirect.com
The worldwide increasing prevalence of obesity and sedentary lifestyle is the main cause of
the rising incidence of T2DM. Due to chronic macrovascular and microvascular …

[HTML][HTML] Risk factors for diabetic retinopathy in northern Chinese patients with type 2 diabetes mellitus

ZP Yan, JX Ma - International journal of ophthalmology, 2016 - ncbi.nlm.nih.gov
AIM To investigate the prevalence and risk factors of diabetic retinopathy (DR) in northern
Chinese patients with type 2 diabetes mellitus (T2DM). METHODS This retrospective cross …

[HTML][HTML] Calcium dobesilate reduces endothelin-1 and high-sensitivity C-reactive protein serum levels in patients with diabetic retinopathy

A Javadzadeh, A Ghorbanihaghjo, FH Adl… - Molecular …, 2013 - ncbi.nlm.nih.gov
Purpose To determine the benefits of calcium dobesilate (CaD) administration on
endothelial function and inflammatory status in patients with diabetic retinopathy through …