This review is a summary of factors affecting the drug pharmacokinetics (PK) of dogs versus
humans. Identifying these interspecies differences can facilitate canine-human PK …

The most common limitation of anticancer chemotherapy is the injury to normal cells.
Cyclophosphamide, which is one of the most widely used alkylating agents, can cause …

Immunotherapy offers a potentially less toxic, more tumor-specific treatment for
neuroblastoma than conventional cytotoxic therapies. Accurate and reproducible immune …

Simple Summary Entry in the metastatic phase is often devastating for cancer patients.
Metastases originate from metastatic progenitor cells that are selected in the primary tumor …

The outcome for children with high-risk neuroblastoma is poor despite intensive multi-modal
treatment protocols. Toxicity from current treatments is significant, and novel approaches are …

Natural polysaccharides have attracted considerable interests due to diverse biological
activities. Succinoglycan is an extracellular polysaccharide produced by most …

Cyclophosphamide (CP) is a widely used anticancer and immunosuppressant drug.
Nevertheless, clinical utilization of CP is limited due to considerable adverse effects and …

Foodborne contaminants are closely related to anthropologic activities and represent an
important food safety hazard. The study of metabolic transformation and toxic side effects of …

Ziyuglycoside I (ZgI), one of the main active ingredients in the popular Diyushengbai tablet
made from Sanguisorba officinalis L., has been proven to relieve leukopenia clinically …

Vinblastine (VBL) is a vinca alkaloid‐class cytotoxic chemotherapeutic that causes
microtubule disruption and is typically used to treat hematologic malignancies. VBL is …