[HTML][HTML] Determinants and outcomes of mitochondrial dynamics

R Quintana-Cabrera, L Scorrano - Molecular Cell, 2023 - cell.com
Mitochondria are not only central organelles in metabolism and energy conversion but are
also platforms for cellular signaling cascades. Classically, the shape and ultrastructure of …

Endoplasmic reticulum stress signals in the tumour and its microenvironment

X Chen, JR Cubillos-Ruiz - Nature Reviews Cancer, 2021 - nature.com
Protein handling, modification and folding in the endoplasmic reticulum (ER) are tightly
regulated processes that determine cell function, fate and survival. In several tumour types …

Mechanisms, regulation and functions of the unfolded protein response

C Hetz, K Zhang, RJ Kaufman - Nature reviews Molecular cell biology, 2020 - nature.com
Cellular stress induced by the abnormal accumulation of unfolded or misfolded proteins at
the endoplasmic reticulum (ER) is emerging as a possible driver of human diseases …

Dysfunctional mitochondria as critical players in the inflammation of autoimmune diseases: Potential role in Sjögren's syndrome

MJ Barrera, S Aguilera, I Castro, P Carvajal, D Jara… - Autoimmunity …, 2021 - Elsevier
Relevant reviews highlight the association between dysfunctional mitochondria and
inflammation, but few studies address the contribution of mitochondria and mitochondria …

Autophagy regulates fatty acid availability for oxidative phosphorylation through mitochondria-endoplasmic reticulum contact sites

C Bosc, N Broin, M Fanjul, E Saland, T Farge… - Nature …, 2020 - nature.com
Autophagy has been associated with oncogenesis with one of its emerging key functions
being its contribution to the metabolism of tumors. Therefore, deciphering the mechanisms of …

Comparative multiplexed interactomics of SARS-CoV-2 and homologous coronavirus nonstructural proteins identifies unique and shared host-cell dependencies

JP Davies, KM Almasy, EF McDonald… - ACS infectious …, 2020 - ACS Publications
Human coronaviruses (hCoVs) have become a threat to global health and society, as
evident from the SARS outbreak in 2002 caused by SARS-CoV-1 and the most recent …

Potential role of mitochondria-associated endoplasmic reticulum membrane proteins in diseases

H Mao, W Chen, L Chen, L Li - Biochemical pharmacology, 2022 - Elsevier
Mitochondria-associated endoplasmic reticulum membranes (MAMs) are dynamic
membrane coupling regions formed by the coupling of the mitochondrial outer membrane …

Photodynamic modulation of endoplasmic reticulum and mitochondria network boosted cancer immunotherapy

X Wang, J Qian, Z Yang, Y Song, W Pan… - Advanced …, 2024 - Wiley Online Library
Immunogenic cell death (ICD) represents a promising approach for enhancing tumor
therapy efficacy by inducing antitumor immune response. However, current ICD inducers …

[HTML][HTML] Call to action to properly utilize electron microscopy to measure organelles to monitor disease

K Neikirk, EG Lopez, AG Marshall, A Alghanem… - European Journal of …, 2023 - Elsevier
This review provides an overview of the current methods for quantifying mitochondrial
ultrastructure, including cristae morphology, mitochondrial contact sites, and recycling …

Myocardial ischemia/reperfusion injury: Mechanisms of injury and implications for management

J He, D Liu, L Zhao, D Zhou… - Experimental and …, 2022 - spandidos-publications.com
Myocardial infarction is one of the primary causes of mortality in patients with coronary heart
disease worldwide. Early treatment of acute myocardial infarction restores blood supply of …