Novel KCNMA1 variants, encoding the BK K+ channel, are associated with a debilitating
dyskinesia and epilepsy syndrome. Neurodevelopmental delay, cognitive disability, and …

Insects are favoured objects for studying information processing in restricted neuronal
networks, eg motor pattern generation or sensory perception. The analysis of the underlying …

In Drosophila, a number of key processes such as emergence from the pupal case,
locomotor activity, feeding, olfaction, and aspects of mating behavior are under circadian …

Animal species display enormous variation for innate behaviours, but little is known about
how this diversity arose. Here, using an unbiased genetic approach, we map a courtship …

The most common form of human autosomal dominant hereditary spastic paraplegia (AD-
HSP) is caused by mutations in the SPG4 (spastin) gene, which encodes an AAA ATPase …

Objective: Autism is a complex, largely genetic psychiatric disorder. In the majority of cases,
the cause of autism is not known, but there is strong evidence for a genetic etiology. To …

Background: Ethanol is one of the most commonly used drugs in the world. We are
interested in the compensatory mechanisms used by the nervous system to counter the …

To explore the use of Caenorhabditis elegans and related nematodes for studying
behavioral evolution, we conducted a comparative study of pharyngeal behaviors and …

Drosophila has proven to be a useful model system for analysis of behavior, including flight.
The initial flight tester involved dropping flies into an oil-coated graduated cylinder; landing …

Tolerance to drugs that affect neural activity is mediated, in part, by adaptive mechanisms
that attempt to restore normal neural excitability. Changes in the expression of ion channel …