Overview of the BioBank Japan Project: Study design and profile
A Nagai, M Hirata, Y Kamatani, K Muto… - Journal of …, 2017 - jstage.jst.go.jp
Background: The BioBank Japan (BBJ) Project was launched in 2003 with the aim of
providing evidence for the implementation of personalized medicine by constructing a large …
providing evidence for the implementation of personalized medicine by constructing a large …
[HTML][HTML] Diversity and inclusion for the All of Us research program: A scoping review
BM Mapes, CS Foster, SV Kusnoor, MI Epelbaum… - PloS one, 2020 - journals.plos.org
The All of Us Research Program (All of Us) is a national effort to accelerate health research
by exploring the relationship between lifestyle, environment, and genetics. It is set to …
by exploring the relationship between lifestyle, environment, and genetics. It is set to …
Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction
Behaviors and disorders related to self-regulation, such as substance use, antisocial
behavior and attention-deficit/hyperactivity disorder, are collectively referred to as …
behavior and attention-deficit/hyperactivity disorder, are collectively referred to as …
[HTML][HTML] GA4GH: International policies and standards for data sharing across genomic research and healthcare
Summary The Global Alliance for Genomics and Health (GA4GH) aims to accelerate
biomedical advances by enabling the responsible sharing of clinical and genomic data …
biomedical advances by enabling the responsible sharing of clinical and genomic data …
[HTML][HTML] Trans-ethnic and ancestry-specific blood-cell genetics in 746,667 individuals from 5 global populations
Most loci identified by GWASs have been found in populations of European ancestry (EUR).
In trans-ethnic meta-analyses for 15 hematological traits in 746,667 participants, including …
In trans-ethnic meta-analyses for 15 hematological traits in 746,667 participants, including …
[HTML][HTML] Mapping ICD-10 and ICD-10-CM codes to phecodes: workflow development and initial evaluation
Background: The phecode system was built upon the International Classification of
Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) for phenome-wide association …
Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) for phenome-wide association …
Multi-ethnic genome-wide association study for atrial fibrillation
C Roselli, MD Chaffin, LC Weng, S Aeschbacher… - Nature …, 2018 - nature.com
Atrial fibrillation (AF) affects more than 33 million individuals worldwide and has a complex
heritability. We conducted the largest meta-analysis of genome-wide association studies …
heritability. We conducted the largest meta-analysis of genome-wide association studies …
A unified framework for joint-tissue transcriptome-wide association and Mendelian randomization analysis
Here, we present a joint-tissue imputation (JTI) approach and a Mendelian randomization
framework for causal inference, MR-JTI. JTI borrows information across transcriptomes of …
framework for causal inference, MR-JTI. JTI borrows information across transcriptomes of …
Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders
Genetic liability to substance use disorders can be parsed into loci that confer general or
substance-specific addiction risk. We report a multivariate genome-wide association meta …
substance-specific addiction risk. We report a multivariate genome-wide association meta …
Predicting risk of suicide attempts over time through machine learning
CG Walsh, JD Ribeiro… - Clinical Psychological …, 2017 - journals.sagepub.com
Traditional approaches to the prediction of suicide attempts have limited the accuracy and
scale of risk detection for these dangerous behaviors. We sought to overcome these …
scale of risk detection for these dangerous behaviors. We sought to overcome these …