[HTML][HTML] Progesterone actions and resistance in gynecological disorders

JA MacLean, K Hayashi - Cells, 2022 - mdpi.com
Estrogen and progesterone and their signaling mechanisms are tightly regulated to maintain
a normal menstrual cycle and to support a successful pregnancy. The imbalance of estrogen …

[HTML][HTML] Endometrial hyperplasia as a risk factor of endometrial cancer

LK Nees, S Heublein, S Steinmacher… - Archives of gynecology …, 2022 - Springer
Endometrial hyperplasia (EH) is the precursor lesion for endometrioid adenocarcinoma of
the endometrium (EC), which represents the most common malignancy of the female …

[HTML][HTML] Therapeutic options for management of endometrial hyperplasia

V Chandra, JJ Kim, DM Benbrook… - Journal of …, 2016 - synapse.koreamed.org
Endometrial hyperplasia (EH) comprises a spectrum of changes in the endometrium ranging
from a slightly disordered pattern that exaggerates the alterations seen in the late …

Oncologic and reproductive outcomes with progestin therapy in women with endometrial hyperplasia and grade 1 adenocarcinoma: a systematic review

CC Gunderson, AN Fader, KA Carson, RE Bristow - Gynecologic oncology, 2012 - Elsevier
OBJECTIVE: The objective of this review was to analyze published contemporary oncologic
and reproductive outcomes in women with endometrial hyperplasia or cancer undergoing …

Endometrial cancer: is this a new disease?

K Moore, MA Brewer - … Society of Clinical Oncology Educational Book, 2017 - ascopubs.org
The incidence of endometrial cancer is increasing, and the age of onset is younger than in
prior years. Although endometrial cancer still occurs more commonly in older women, for …

Non-contraceptive benefits of hormonal and intrauterine reversible contraceptive methods

L Bahamondes, M Valeria Bahamondes… - Human reproduction …, 2015 - academic.oup.com
BACKGROUND Most contraceptive methods present benefits beyond contraception;
however, despite a large body of evidence, many healthcare professionals (HCPs), users …

Management of endometrial precancers

CL Trimble, M Leitao, K Lu, O Ioffe… - Obstetrics & …, 2012 - journals.lww.com
Abstract In the United States, endometrial cancer is the most commonly diagnosed cancer of
the female reproductive system. Strategies to sensitively and accurately diagnose …

Oral progestogens vs levonorgestrel-releasing intrauterine system for endometrial hyperplasia: a systematic review and metaanalysis

ID Gallos, M Shehmar, S Thangaratinam… - American journal of …, 2010 - Elsevier
OBJECTIVE:: To conduct a systematic review and metaanalysis of studies evaluating the
regression rate of endometrial hyperplasia with oral progestogens and levonorgestrel …

Role of progesterone in endometrial cancer

JJ Kim, E Chapman-Davis - Seminars in reproductive medicine, 2010 - thieme-connect.com
Progesterone is a key hormone in the endometrium that opposes estrogen-driven growth.
Insufficient progesterone will result in unopposed estrogen action that could lead to the …

Hysteroscopic endometrial focal resection followed by levonorgestrel intrauterine device insertion as a fertility-sparing treatment of atypical endometrial hyperplasia …

P Giampaolino, ADS Sardo, A Mollo, A Raffone… - Journal of Minimally …, 2019 - Elsevier
Abstract Study Objective To evaluate safety and effectiveness of the combination of
hysteroscopic endometrial focal resection with levonorgestrel-releasing intrauterine device …