NF-κB signaling in skeletal muscle health and disease

JM Peterson, N Bakkar, DC Guttridge - Current topics in developmental …, 2011 - Elsevier
Muscle development, growth, and maintenance require an intricate and timely series of
events initiated through a multitude of signaling pathways. The very nature of skeletal …

Synaptic NF-kappa B pathway in neuronal plasticity and memory

A Salles, A Romano, R Freudenthal - Journal of Physiology-Paris, 2014 - Elsevier
Several transcription factors are present at the synapse, and among these are the Rel-NF-
kappa B pathway components. NF-kappa B is a constitutive transcription factor, with a strong …

The Links between ALS and NF-κB

E Källstig, BD McCabe, BL Schneider - International Journal of Molecular …, 2021 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease wherein motor neuron
degeneration leads to muscle weakness, progressive paralysis, and death within 3–5 years …

Agrin-LRP4-MuSK signaling as a therapeutic target for myasthenia gravis and other neuromuscular disorders

K Ohno, B Ohkawara, M Ito - Expert Opinion on Therapeutic Targets, 2017 - Taylor & Francis
Introduction: Signal transduction at the neuromuscular junction (NMJ) is compromised in a
diverse array of diseases including myasthenia gravis, Lambert-Eaton myasthenic …

Decreased Neuromuscular Function and Muscle Quality along with Increased Systemic Inflammation and Muscle Proteolysis Occurring in the Presence of Decreased …

DS Willoughby, C Florez, J Davis, N Keratsopoulos… - Nutrients, 2024 - mdpi.com
Menopause causes a reduction in estradiol (E2) and may be associated with neuromuscular
degeneration. Compared to pre-menopausal (PRE-M) women, this study sought to …

An NF-κB-EphrinA5-dependent communication between NG2+ interstitial cells and myoblasts promotes muscle growth in neonates

JM Gu, DJ Wang, JM Peterson, J Shintaku… - Developmental cell, 2016 - cell.com
Skeletal muscle growth immediately following birth is critical for proper body posture and
locomotion. However, compared with embryogenesis and adulthood, the processes …

Transcriptional networks regulating the costamere, sarcomere, and other cytoskeletal structures in striated muscle

NL Estrella, FJ Naya - Cellular and molecular life sciences, 2014 - Springer
Structural abnormalities in striated muscle have been observed in numerous transcription
factor gain-and loss-of-function phenotypes in animal and cell culture model systems …

[HTML][HTML] Cytisine induces apoptosis of HepG2 cells

L Yu, X Wang, ZF Chen, B Jiang… - Molecular …, 2017 - spandidos-publications.com
Cytisine is a quinolizidine alkaloid, which has been reported to be among the major
bioactive components of Sophora alopecuraides L. Quinolizidine alkaloids have previously …

[HTML][HTML] Gene Expression of Neurogenesis Related to Exercise Intensity in a Cerebral Infarction Rat Model

MK Song, HS Jo, EJ Kim, JK Kim, SG Lee - International Journal of …, 2024 - mdpi.com
Regular exercise improves several functions, including cognition, in patients with stroke.
However, the effect of regular exercise on neurogenesis related to cognition remains …

[HTML][HTML] Mesdc2 plays a key role in cell-surface expression of Lrp4 and postsynaptic specialization in myotubes

T Hoshi, T Tezuka, K Yokoyama, S Iemura, T Natsume… - FEBS letters, 2013 - Elsevier
Low-density lipoprotein receptor-related protein 4 (Lrp4) is essential for pre-and post-
synaptic specialization at the neuromuscular junction (NMJ), an indispensable synapse …