CysK (O-acetylserine sulfhydrylase) is a pyridoxal-5′ phosphate-dependent enzyme which
catalyzes the second step of the de novo cysteine biosynthesis pathway by converting O …

Leishmaniasis, one of the most prevalent yet neglected parasitic causes of death, yearns for
therapeutic control and treatment. Severely toxic and inefficient modern-day pentavalent …

The reverse transsulfuration pathway has been reported to produce cysteine from
homocysteine in eukaryotes ranging from protozoans to mammals while bacteria and plants …

Amoebiasis, a widespread disease caused by the protozoan parasite Entamoeba histolytica,
poses challenges due to the adverse effects of existing antiamoebic drugs and rising drug …

The l-cysteine is crucial for growth, survival, defense against oxidative stress, and
pathogenesis of Entamoeba histolytica. The de novo biosynthesis of l-cysteine in E …

O‐acetylserine sulfhydrylase (OASS) and cystathionine β‐synthase (CBS) are members of
the PLP‐II family, and involved in L‐cysteine production. OASS produces L‐cysteine via a …

Brucella ovis is an ovine intracellular pathogen with tropism for the male genital tract. To
establish and maintain infection, B. ovis must survive stressful conditions inside host cells …

In most bacteria and plants, direct biosynthesis of cysteine from sulfide via O-acetylserine
(OAS) is essential to produce sulfur amino acids from inorganic sulfur. Here, we report the …

Amoebiasis is a common parasitic infection in the developing world and is caused by the
protist Entameoba histolytica. The proliferation of E. histolytica and its ability to invade …

Cysteine is implicated in important biological processes. It is synthesized through two
different pathways. Cystathionine β‐synthase and cystathionine γ‐lyase participate in the …