Understanding ubiquitination in neurodevelopment by integrating insights across space and time

MC Ambrozkiewicz, S Lorenz - Nature Structural & Molecular Biology, 2024 - nature.com
Ubiquitination regulates a myriad of eukaryotic signaling cascades by modifying substrate
proteins, thereby determining their functions and fates. In this perspective, we discuss …

The E3 ubiquitin ligase ITCH negatively regulates intercellular communication via gap junctions by targeting connexin43 for lysosomal degradation

MZ Totland, LM Knudsen, NL Rasmussen… - Cellular and Molecular …, 2024 - Springer
Intercellular communication via gap junctions has a fundamental role in regulating cell
growth and tissue homeostasis, and its dysregulation may be involved in cancer …