Organisms of all domains of life use photoreceptor proteins to sense and respond to light.
The light-sensitivity of photoreceptor proteins arises from bound chromophores such as …

G protein-coupled receptors (GPCRs) transduce a wide array of extracellular signals and
regulate virtually every aspect of physiology. While GPCR signaling is essential …

G protein-coupled receptors (GPCRs) are responsible for the majority of cellular responses
to hormones and neurotransmitters as well as the senses of sight, olfaction and taste. The …

G-protein-coupled receptors (GPCRs) mediate most of our physiological responses to
hormones, neurotransmitters and environmental stimulants, and so have great potential as …

The parasympathetic branch of the autonomic nervous system regulates the activity of
multiple organ systems. Muscarinic receptors are G-protein-coupled receptors that mediate …

Seven-transmembrane receptors, which constitute the largest, most ubiquitous and most
versatile family of membrane receptors, are also the most common target of therapeutic …

To be considered in this discussion is a family of guanine nucleotide-binding proteins (G
proteins) that serve as membrane-bound transducers of chemically and physically coded …

G protein-coupled receptors (GPCRs) are the largest family of membrane-bound receptors
and also the targets of many drugs. Understanding of the functional significance of the wide …

Ca2+ plays a crucial role in connecting membrane excitability with contraction in
myocardium. The hallmark features of heart failure are mechanical dysfunction and …

History suggests β agonists, the cognate ligand of the β 2 adrenoceptor, have been used as
bronchodilators for around 5,000 years, and β agonists remain today the frontline treatment …