Tens of millions of contrast-enhanced magnetic resonance imaging (MRI) exams are
performed annually around the world. The contrast agents, which improve diagnostic …

Contrast-enhanced magnetic resonance imaging (MRI) is an indispensable tool for
diagnostic medicine. However, safety concerns related to gadolinium in commercial MRI …

High-grade gliomas, the most common and aggressive primary brain tumors, are
characterized by a complex tumor microenvironment (TME). Among the immune cells …

Visualization of biological targets such as crucial cells and biomolecules in living subjects is
critical for the studies of important biological processes. Though 1H magnetic resonance …

Abstract Purpose: Tumor-associated macrophages (TAMs) in malignant tumors have been
linked to tumor aggressiveness and represent a new target for cancer immunotherapy. As …

Imaging and tracking macrophage behaviors in vivo are essential to reveal its biological
function and fate in various diseases. Small molecular probes suffer from poor macrophage …

The innate immune system plays a key role as the first line of defense in various human
diseases including cancer, cardiovascular and inflammatory diseases. In contrast to tissue …

Purpose A bottleneck in developing cell therapies for cancer is assaying cell biodistribution,
persistence, and survival in vivo. Ex vivo cell labeling using perfluorocarbon (PFC) …

Tumor-associated macrophages (TAMs) in the tumor microenvironment potentially enhance
tumor growth and invasion through various mechanisms and are thus an essential factor in …

Tumor-associated macrophages (TAMs), the most abundant inflammatory cell group in the
tumor microenvironment, play an essential role in tumor immune regulation. The infiltration …