Cholangiocarcinoma (CCA) is a highly lethal adenocarcinoma of the hepatobiliary system,
which can be classified as intrahepatic, perihilar and distal. Each anatomic subtype has …

Bacteria identified in the oral cavity are highly complicated. They include approximately
1000 species with a diverse variety of commensal microbes that play crucial roles in the …

Cancer may be induced by many environmental and physiological conditions. Infections
with viruses, bacteria and parasites have been recognized for years to be associated with …

The association of cancer and diabetes mellitus (DM) has been studied for decades.
Hyperglycemia and the imbalance of hormones are factors that contribute to the molecular …

Increased glucose utilization is a feature of cancer cells to support cell survival, proliferation,
and metastasis. An association between diabetes mellitus and cancer progression was …

Epidemiological studies have indicated diabetes mellitus (DM) as a risk of
cholangiocarcinoma (CCA), however, the effects and mechanisms of high glucose on …

Intrahepatic cholangiocarcinoma (iCCA) is a highly aggressive cancer with marked
resistance to chemotherapeutics without therapies. The tumour microenvironment of iCCA is …

Background/Aim: Cholangiocarcinoma (CCA) is an aggressive cancer for which standard
treatments are still ineffective. This study demonstrated the antiproliferative and anti …

BACKGROUND The association between diabetes mellitus (DM) and the increased risk and
progression of cholangiocarcinoma (CCA) has been reported with unclear underlying …

Background Cholangiocarcinoma (CCA) is a category of lethal hepatobiliary malignancies.
Previous studies have found that Opisthorchis viverrini infection and diabetes mellitus (DM) …