Key events in cellular trafficking occur at the cell surface, and it is desirable to visualize
these events without interference from other regions deeper within. This review describes a …

Regulated exocytosis of secretory granules or dense-core granules has been examined in
many well-characterized cell types including neurons, neuroendocrine, endocrine, exocrine …

Publisher Summary Total internal reflection fluorescence (TIRF) provides a means to
selectively excite just those fluorophores in an aqueous environment that are very near a …

Publisher Summary This chapter describes the total internal reflection fluorescence (TIRF)
microscopy in cell biology. TIRF microscopy (also called “evanescent wave microscopy”) …

Evanescent wave microscopy, also termed total internal reflection fluorescence microscopy
(TIR-FM), has shed new light on important cellular processes taking place near the plasma …

Total internal reflection fluorescence microscopy (TIRFM), also known as evanescent wave
microscopy, is used in a wide range of applications, particularly to view single molecules …

Many neurosecretory preparations display two components of depolarization-induced
exocytosis: a phasic component synchronized with Ca 2+ channel opening, followed by a …

In chromaffin cells the number of large dense‐core vesicles (LDCVs) which can be released
by brief, intense stimuli represents only a small fraction of the 'morphologically …

A simple input–output formalism based on the Lorentz reciprocity theorem is presented for
the study of a classical radiating dipole near a lossless interface. The problems of dipole …

Peptidergic neurotransmission is slow compared to that mediated by classical
neurotransmitters. We have studied exocytotic membrane fusion and cargo release by …