Bioactive materials promote wound healing through modulation of cell behaviors

R Li, K Liu, X Huang, D Li, J Ding, B Liu… - Advanced …, 2022 - Wiley Online Library
Skin wound repair is a multistage process involving multiple cellular and molecular
interactions, which modulate the cell behaviors and dynamic remodeling of extracellular …

Polymer-based wound dressing materials loaded with bioactive agents: Potential materials for the treatment of diabetic wounds

S Alven, S Peter, Z Mbese, BA Aderibigbe - Polymers, 2022 - mdpi.com
Diabetic wounds are severe injuries that are common in patients that suffer from diabetes.
Most of the presently employed wound dressing scaffolds are inappropriate for treating …

Umbilical cord-derived mesenchymal stem cell-derived exosomes combined pluronic F127 hydrogel promote chronic diabetic wound healing and complete skin …

J Yang, Z Chen, D Pan, H Li, J Shen - International journal of …, 2020 - Taylor & Francis
Purpose Chronic refractory wounds are a multifactorial comorbidity of diabetes mellitus with
the characteristic of impaired vascular networks. Currently, there is a lack of effective …

Exosome laden oxygen releasing antioxidant and antibacterial cryogel wound dressing OxOBand alleviate diabetic and infectious wound healing

PA Shiekh, A Singh, A Kumar - Biomaterials, 2020 - Elsevier
Lack of oxygen, reduced vascularization, elevated oxidative stress, and infection are critical
clinical hallmarks of non-healing chronic diabetic wounds. Therefore, delivering oxygen …

Biomimetic hydrogels to promote wound healing

F Fan, S Saha, D Hanjaya-Putra - Frontiers in Bioengineering and …, 2021 - frontiersin.org
Wound healing is a common physiological process which consists of a sequence of
molecular and cellular events that occur following the onset of a tissue lesion in order to …

Poloxamer: A versatile tri-block copolymer for biomedical applications

P Zarrintaj, JD Ramsey, A Samadi, Z Atoufi, MK Yazdi… - Acta biomaterialia, 2020 - Elsevier
Poloxamers, also called Pluronic, belong to a unique class of synthetic tri-block copolymers
containing central hydrophobic chains of poly (propylene oxide) sandwiched between two …

Topical gel-based biomaterials for the treatment of diabetic foot ulcers

JR Bardill, MR Laughter, M Stager, KW Liechty… - Acta biomaterialia, 2022 - Elsevier
Diabetic foot ulcers (DFUs) are a devastating ailment for many diabetic patients with
increasing prevalence and morbidity. The complex pathophysiology of DFU wound …

In situ formation of injectable hydrogels for chronic wound healing

Y Gao, Z Li, J Huang, M Zhao, J Wu - Journal of Materials Chemistry B, 2020 - pubs.rsc.org
Hydrogels have been widely used in wound healing treatment over the past decade.
Injectable hydrogels have become a major research focus due to their unique advantages …

Human adipose-derived mesenchymal stem cells-derived exosomes encapsulated in pluronic F127 hydrogel promote wound healing and regeneration

Y Zhou, XL Zhang, ST Lu, NY Zhang, HJ Zhang… - Stem cell research & …, 2022 - Springer
Background Large area skin trauma has always been a great challenge for both patients
and clinicians. Exosomes originating from human adipose-derived mesenchymal stem cells …

Novel trends in application of stem cells in skin wound healing

M Kucharzewski, E Rojczyk… - European journal of …, 2019 - Elsevier
The latest findings indicate the huge therapeutic potential of stem cells in regenerative
medicine, including the healing of chronic wounds. Main stem cell types involved in wound …