Genetics and epigenetics in asthma
P Ntontsi, A Photiades, E Zervas, G Xanthou… - International journal of …, 2021 - mdpi.com
Asthma is one of the most common respiratory disease that affects both children and adults
worldwide, with diverse phenotypes and underlying pathogenetic mechanisms poorly …
worldwide, with diverse phenotypes and underlying pathogenetic mechanisms poorly …
Targeting cell signaling in allergic asthma
SS Athari - Signal transduction and targeted therapy, 2019 - nature.com
Asthma is chronic inflammation of the airways characterized by airway hyper-
responsiveness, wheezing, cough, and dyspnea. Asthma affects> 350 million people …
responsiveness, wheezing, cough, and dyspnea. Asthma affects> 350 million people …
Spotlight on microRNAs in allergy and asthma
In past 10 years, microRNAs (miRNAs) have gained scientific attention due to their
importance in the pathophysiology of allergic diseases and their potential as biomarkers in …
importance in the pathophysiology of allergic diseases and their potential as biomarkers in …
Genetics and epigenetics in allergic rhinitis
BY Choi, M Han, JW Kwak, TH Kim - Genes, 2021 - mdpi.com
The pathogenesis of allergic rhinitis is associated with genetic, environmental, and
epigenetic factors. Genotyping of single nucleotide polymorphisms (SNPs) is an advanced …
epigenetic factors. Genotyping of single nucleotide polymorphisms (SNPs) is an advanced …
Diagnostic, functional, and therapeutic roles of microRNA in allergic diseases
TX Lu, ME Rothenberg - Journal of Allergy and Clinical Immunology, 2013 - Elsevier
Allergic inflammation is accompanied by the coordinated expression of a myriad of genes
and proteins that initiate, sustain, and propagate immune responses and tissue remodeling …
and proteins that initiate, sustain, and propagate immune responses and tissue remodeling …
The roles of miRNAs as potential biomarkers in lung diseases
MicroRNAs (miRNAs) are small non-coding RNAs which can act as master regulators of
gene expression, modulate almost all biological process and are essential for maintaining …
gene expression, modulate almost all biological process and are essential for maintaining …
Dnmt3a restrains mast cell inflammatory responses
C Leoni, S Montagner, A Rinaldi… - Proceedings of the …, 2017 - National Acad Sciences
DNA methylation and specifically the DNA methyltransferase enzyme DNMT3A are involved
in the pathogenesis of a variety of hematological diseases and in regulating the function of …
in the pathogenesis of a variety of hematological diseases and in regulating the function of …
Role of microRNAs in lung development and pulmonary diseases
MicroRNAs (miRNAs) are a class of small noncoding RNA which exert post-transcriptional
gene regulation activity by targeting messenger RNAs. miRNAs have been found to be …
gene regulation activity by targeting messenger RNAs. miRNAs have been found to be …
Vesicular trafficking and signaling for cytokine and chemokine secretion in mast cells
U Blank, IK Madera-Salcedo, L Danelli… - Frontiers in …, 2014 - frontiersin.org
Upon activation mast cells (MCs) secrete numerous inflammatory compounds stored in their
cytoplasmic secretory granules by a process called anaphylactic degranulation, which is …
cytoplasmic secretory granules by a process called anaphylactic degranulation, which is …
MicroRNA regulation of allergic inflammation and asthma
HH Pua, KM Ansel - Current Opinion in Immunology, 2015 - Elsevier
Highlights•miRNAs regulate allergic inflammation and allergic responses.•miRNAs act
coordinately through target gene networks.•miRNAs impact diverse cellular functions in type …
coordinately through target gene networks.•miRNAs impact diverse cellular functions in type …