Sarcoma

KM Skubitz, DR D'Adamo - Mayo Clinic Proceedings, 2007 - Elsevier
Sarcomas comprise a heterogeneous group of mesenchymal neoplasms. They can be
grouped into 2 general categories, soft tissue sarcoma and primary bone sarcoma, which …

Radiotherapy for management of extremity soft tissue sarcomas: why, when, and where?

RLM Haas, TF DeLaney, B O'Sullivan, RB Keus… - International Journal of …, 2012 - Elsevier
This critical review will focus on published data on the indications for radiotherapy in
patients with extremity soft tissue sarcomas and its role in local control, survival, and …

Radiation therapy for treatment of soft tissue sarcoma in adults: executive summary of an ASTRO clinical practice guideline

KE Salerno, KM Alektiar, EH Baldini, M Bedi… - Practical radiation …, 2021 - Elsevier
Purpose This guideline provides evidence-based recommendations addressing the
indications for radiation therapy (RT), sequencing of local therapies, and appropriate dose …

Soft tissue sarcoma, version 2.2016, NCCN clinical practice guidelines in oncology

M Von Mehren, RL Randall, RS Benjamin… - Journal of the National …, 2016 - jnccn.org
Soft tissue sarcomas (STS) are rare solid tumors of mesenchymal cell origin that display a
heterogenous mix of clinical and pathologic characteristics. STS can develop from fat …

Guidelines for the management of soft tissue sarcomas

R Grimer, I Judson, D Peake, B Seddon - Sarcoma, 2010 - Wiley Online Library
These guidelines were drawn up following a consensus meeting of UK sarcoma specialists
convened under the auspices of the British Sarcoma Group and are intended to provide a …

Late radiation morbidity following randomization to preoperative versus postoperative radiotherapy in extremity soft tissue sarcoma

AM Davis, B O'Sullivan, R Turcotte, R Bell… - Radiotherapy and …, 2005 - Elsevier
BACKGROUND AND PURPOSE: This study compared late radiation morbidity in patients
with extremity soft tissue sarcoma randomized to treatment by pre-(50Gy) or postoperative …

Phase 2 study of preoperative image‐guided intensity‐modulated radiation therapy to reduce wound and combined modality morbidities in lower extremity soft tissue …

B O'Sullivan, AM Griffin, CI Dickie, MB Sharpe… - Cancer, 2013 - Wiley Online Library
BACKGROUND: This study sought to determine if preoperative image‐guided intensity‐
modulated radiotherapy (IG‐IMRT) can reduce morbidity, including wound complications, by …

Local therapy in localized Ewing tumors: results of 1058 patients treated in the CESS 81, CESS 86, and EICESS 92 trials

A Schuck, S Ahrens, M Paulussen, M Kuhlen… - International Journal of …, 2003 - Elsevier
Purpose: The impact of different local therapy approaches on local control, event-free
survival, and secondary malignancies in the CESS 81, CESS 86, and EICESS 92 trials was …

The effect of the setting of a positive surgical margin in soft tissue sarcoma

PW O'Donnell, AM Griffin, WC Eward, A Sternheim… - Cancer, 2014 - Wiley Online Library
BACKGROUND The objectives of this study were to evaluate the risk of local recurrence and
survival after soft tissue sarcoma (STS) resection with positive margins and to evaluate the …

Neoadjuvant chemotherapy in soft tissue sarcomas: latest evidence and clinical implications

S Pasquali, A Gronchi - Therapeutic advances in medical …, 2017 - journals.sagepub.com
Soft tissue sarcomas are a rare and multifaceted group of solid tumours. Neoadjuvant
chemotherapy is increasingly used to limit loss of function after wide surgical excision with …