Cancer biomarkers and their biosensors: A comprehensive review

H Khan, MR Shah, J Barek, MI Malik - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
The article starts with a brief history of discovery of cancer biomarkers followed by statistical
data on published cancer biomarkers detection strategies in the last decade to demonstrate …

Non-invasive biomarkers for early detection of breast cancer

J Li, X Guan, Z Fan, LM Ching, Y Li, X Wang, WM Cao… - Cancers, 2020 - mdpi.com
Simple Summary Early diagnosis of breast cancer greatly increases the chance of cure and
survival from the disease. The mammogram is widely used for early detection of breast …

Metabolomics for laboratory diagnostics

R Bujak, W Struck-Lewicka, MJ Markuszewski… - … of pharmaceutical and …, 2015 - Elsevier
Metabolomics is an emerging approach in a systems biology field. Due to continuous
development in advanced analytical techniques and in bioinformatics, metabolomics has …

[PDF][PDF] High resolution mass spectrometry improves data quantity and quality as compared to unit mass resolution mass spectrometry in high-throughput profiling …

AM Evans, BR Bridgewater, Q Liu, MW Mitchell… - …, 2014 - researchgate.net
Metabolomics is a technique in which the small molecule component from a biological
source material is analyzed for changes resulting from some set of test conditions. Liquid …

Integrated, nontargeted ultrahigh performance liquid chromatography/electrospray ionization tandem mass spectrometry platform for the identification and relative …

AM Evans, CD DeHaven, T Barrett, M Mitchell… - Analytical …, 2009 - ACS Publications
To address the challenges associated with metabolomics analyses, such as identification of
chemical structures and elimination of experimental artifacts, we developed a platform that …

Metabolomics for biomarker discovery: moving to the clinic

A Zhang, H Sun, G Yan, P Wang… - Biomed research …, 2015 - Wiley Online Library
To improve the clinical course of diseases, more accurate diagnostic and assessment
methods are required as early as possible. In order to achieve this, metabolomics offers new …

Mass spectrometric based approaches in urine metabolomics and biomarker discovery

MM Khamis, DJ Adamko… - Mass spectrometry …, 2017 - Wiley Online Library
Urine metabolomics has recently emerged as a prominent field for the discovery of non‐
invasive biomarkers that can detect subtle metabolic discrepancies in response to a specific …

Capillary electrophoresis mass spectrometry-based saliva metabolomics identified oral, breast and pancreatic cancer-specific profiles

M Sugimoto, DT Wong, A Hirayama, T Soga, M Tomita - Metabolomics, 2010 - Springer
Saliva is a readily accessible and informative biofluid, making it ideal for the early detection
of a wide range of diseases including cardiovascular, renal, and autoimmune diseases, viral …

Metabolomics in cancer biomarker discovery: current trends and future perspectives

EG Armitage, C Barbas - Journal of pharmaceutical and biomedical …, 2014 - Elsevier
Cancer is one of the most devastating human diseases that causes a vast number of
mortalities worldwide each year. Cancer research is one of the largest fields in the life …

Chemometrics in metabolomics—a review in human disease diagnosis

R Madsen, T Lundstedt, J Trygg - Analytica chimica acta, 2010 - Elsevier
Metabolomics is a post genomic research field concerned with developing methods for
analysis of low molecular weight compounds in biological systems, such as cells, organs or …