Hyaluronic acid: A key ingredient in the therapy of inflammation

A Marinho, C Nunes, S Reis - Biomolecules, 2021 - mdpi.com
Hyaluronic acid (HA) is a natural polymer, produced endogenously by the human body,
which has unique physicochemical and biological properties, exhibiting desirable …

Animal models of interstitial cystitis/bladder pain syndrome

C Tay, L Grundy - Frontiers in Physiology, 2023 - frontiersin.org
Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) is a chronic disorder characterized by
pelvic and/or bladder pain, along with lower urinary tract symptoms that have a significant …

Oral Preparation of Hyaluronic Acid, Chondroitin Sulfate, Curcumin, and Quercetin (Ialuril® Soft Gels) for the Prevention of LUTS after Intravesical Chemotherapy

C Manfredi, L Spirito, FP Calace, R Balsamo… - Pathophysiology, 2022 - mdpi.com
Intravesical chemotherapy may cause chemical cystitis and related lower urinary tract
symptoms (LUTS). The aims of this study were to evaluate the efficacy and safety of an oral …

Rosmarinic acid ameliorates HCl-induced cystitis in rats

N Kitamura, Y Yamamoto, N Yamamoto, T Murase - PloS One, 2023 - journals.plos.org
Shiso (Perilla frutescens var crispa f. purprea) is a traditional medicinal herb that exerts anti-
inflammatory effects and alleviates lower urinary tract symptoms. In this study, we examined …

Changes in cystoscopic findings after intravesical hyaluronic acid instillation therapy in patients with interstitial cystitis

CJ Lin, CK Liu, HY Hsieh, MJ Chen, CP Tsai - Diagnostics, 2022 - mdpi.com
(1) Background: Limited data showed changes in glomerulation in the bladder mucosa of
patients with interstitial cystitis (IC) after intravesical hyaluronic acid (HA) bladder infusion …

Divergent histopathological and molecular patterns in chemically induced interstitial cystitis/bladder pain syndrome rat models

YC Chang, CY Yu, C Dong, SL Chen, WW Sung - Scientific Reports, 2024 - nature.com
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a complex chronic pain disorder with
an elusive etiology and nonspecific symptoms. Although numerous animal models with …

Effect of Glycosaminoglycan Replacement on Markers of Interstitial Cystitis In Vitro

P Rooney, C Ryan, BJ McDermott, K Dev… - Frontiers in …, 2020 - frontiersin.org
Aims: To examine the effect of three commercial intravesical formulations of
glycosaminoglycan on in vitro inflammatory models of IC/BPS to better understand there …

Preliminary evidence for therapeutic impact of intravesical glucosamine on protamine sulfate and potassium chloride-induced bladder overactivity in rat model

SH Lu, TF Yun, YR Kou, YP Chang - World Journal of Urology, 2024 - Springer
Purpose To investigate the protective effect of intravesical glucosamine in treating overactive
bladder (OAB). Methods Ninety-two female Sprague–Dawley (SD) rats were divided into 4 …

Efek Simvastatin terhadap Urin dan Jaringan Buli-Buli pada Tikus Model Sistitis Interstisial Akut yang Diinduksi Protamin Sulfat

ADI Hasanuddin, R Minhajat… - Alami Journal …, 2023 - journal3.uin-alauddin.ac.id
The pathophysiology of interstitial cystitis (IC) is complicated and related to statin drug use
without any established underlying mechanisms. This study used a rat model of acute IC …

尿标记物和影像学在间质性膀胱炎/膀胱疼痛综合征诊断中的潜在价值

马凯群, 张嘉鹏, 郑振明, 姚友生 - 临床泌尿外科杂志, 2019 - whuhzzs.com
间质性膀胱炎/膀胱疼痛综合征(IC/BPS) 是一种病因尚未完全明确的疾病, 目前提出的病因包括
感染, 自身免疫/炎症, 肥大细胞, 膀胱氨基葡聚糖和上皮渗透性, 神经支配, 尿液毒性物质等 …