The growing availability of more effective therapies has contributed to an increased survival
of patients with breast cancer. In hormone receptor-positive early disease, increased …

Long-term survival rates after a diagnosis of breast cancer are steadily rising. This is good
news, but clinicians must also recognize that this brings new challenges to the medical …

Highlights•Breast cancer in young women should be treated based on stage and biology of
disease.•Management of breast cancer in young women requires special considerations …

Purpose To update the ASCO clinical practice guideline on adjuvant endocrine therapy on
the basis of emerging data on the optimal duration of treatment, particularly adjuvant …

Breast cancer arising at a young age is relatively uncommon, particularly in the developed
world. Several studies have demonstrated that younger patients often experience a more …

Background. Oral antineoplastic therapies not only improve survival but also reduce the
burden of care for patients. Yet patients and clinicians face new challenges in managing …

Cell state transitions control the functional behavior of cancer cells. Epithelial-to-
mesenchymal transition (EMT) confers cancer stem cell-like properties, enhanced …

Each year Clinical Cancer Advances: ASCO's Annual Report on Progress Against Cancer
highlights the most important clinical research advances of the past year, including the …

Purpose Arthralgia occurs in up to 50% of breast cancer survivors treated with aromatase
inhibitors (AIs) and is the most common reason for poor AI adherence. We conducted, in 121 …

Purpose To investigate adherence to endocrine treatment and its relationship with disease-
free survival (DFS) in the Breast International Group (BIG) 1-98 clinical trial. Methods The …