Anti-cancer peptide-based therapeutic strategies in solid tumors
M Karami Fath, K Babakhaniyan, M Zokaei… - Cellular & Molecular …, 2022 - Springer
Background Nowadays, conventional medical treatments such as surgery, radiotherapy, and
chemotherapy cannot cure all types of cancer. A promising approach to treat solid tumors is …
chemotherapy cannot cure all types of cancer. A promising approach to treat solid tumors is …
Peptide-based agents for cancer treatment: current applications and future directions
Peptide-based strategies have received an enormous amount of attention because of their
specificity and applicability. Their specificity and tumor-targeting ability are applied to …
specificity and applicability. Their specificity and tumor-targeting ability are applied to …
Nanotechnology‐based electrochemical biosensors for monitoring breast cancer biomarkers
H Nasrollahpour, B Khalilzadeh… - Medicinal Research …, 2023 - Wiley Online Library
Breast cancer is categorized as the most widespread cancer type among women globally.
On‐time diagnosis can decrease the mortality rate by making the right decision in the …
On‐time diagnosis can decrease the mortality rate by making the right decision in the …
MOrPH-PhD: an integrated phage display platform for the discovery of functional genetically encoded peptide macrocycles
Macrocyclic peptides represent attractive scaffolds for targeting protein–protein interactions,
making methods for the diversification and functional selection of these molecules highly …
making methods for the diversification and functional selection of these molecules highly …
In Vitro Selection of Peptides and Proteins—Advantages of mRNA Display
mRNA display is a robust in vitro selection technique that allows the selection of peptides
and proteins with desired functions from libraries of trillions of variants. mRNA display relies …
and proteins with desired functions from libraries of trillions of variants. mRNA display relies …
Fanconi anemia pathway as a prospective target for cancer intervention
Fanconi anemia (FA) is a recessive genetic disorder caused by biallelic mutations in at least
one of 22 FA genes. Beyond its pathological presentation of bone marrow failure and …
one of 22 FA genes. Beyond its pathological presentation of bone marrow failure and …
Display selection of exotic macrocyclic peptides expressed under a radically reprogrammed 23 amino acid genetic code
T Passioura, W Liu, D Dunkelmann… - Journal of the …, 2018 - ACS Publications
Bioactive naturally occurring macrocyclic peptides often exhibit a strong bias for
hydrophobic residues. Recent advances in in vitro display technologies have made possible …
hydrophobic residues. Recent advances in in vitro display technologies have made possible …
Expanding the chemical diversity of genetically encoded libraries
SE Iskandar, VA Haberman… - ACS combinatorial …, 2020 - ACS Publications
The power of ribosomes has increasingly been harnessed for the synthesis and selection of
molecular libraries. Technologies, such as phage display, yeast display, and mRNA display …
molecular libraries. Technologies, such as phage display, yeast display, and mRNA display …
Highly Constrained Bicyclic Scaffolds for the Discovery of Protease-Stable Peptides via mRNA Display
Highly constrained peptides such as the knotted peptide natural products are promising
medicinal agents because of their impressive biostability and potent activity. Yet, libraries of …
medicinal agents because of their impressive biostability and potent activity. Yet, libraries of …
Isolation, Cytotoxicity Evaluation, Docking, ADMET and Drug Likeness Studies of Secondary Metabolites from the Stem Bark of Anthocephalus cadamba (Roxb.)
Phytochemical investigation of the stem bark of Anthocephalus cadamba (Rubiaceae) led to
the isolation of total ten secondary metabolites (1‐10) including β–sitosterol (1), ursolic acid …
the isolation of total ten secondary metabolites (1‐10) including β–sitosterol (1), ursolic acid …