Because of its profound effects on the rates of biological processes such as aerobic
metabolism, environmental temperature plays an important role in shaping the distribution …

Many studies now produce parallel data sets from different omics technologies; however, the
task of interpreting the acquired data in an integrated fashion is not trivial. This review covers …

Metabolomics aims to provide a global snapshot of all small-molecule metabolites in cells
and biological fluids, free of observational biases inherent to more focused studies of …

In this postgenomic era, there is a specific need to assign function to orphan genes in order
to validate potential targets for drug therapy and to discover new biomarkers of disease …

Pancreatic cancer (PC) is one of the most lethal malignancies. Recent studies indicate that
patients with incidentally diagnosed PC have better prognosis than those with symptoms …

The primary aim of “omic” technologies is the nontargeted identification of all gene products
(transcripts, proteins, and metabolites) present in a specific biological sample. By their …

Recent advances in various 'omics' technologies enable quantitative monitoring of the
abundance of various biological molecules in a high-throughput manner, and thus allow …

In the post-genomic era, several profiling tools have been developed to provide a more
comprehensive picture of tumour development and progression. The global analysis of …

When conditions change, unicellular organisms rewire their metabolism to sustain cell
maintenance and cellular growth. Such rewiring may be understood as resource re …

The ability to sequence whole genomes has taught us that our knowledge with respect to
gene function is rather limited with typically 30–40% of open reading frames having no …