Enzymes of the cyclooxygenase pathways of prostanoid biosynthesis
WL Smith, Y Urade, PJ Jakobsson - Chemical reviews, 2011 - ACS Publications
Prostanoids are cyclic, oxygenated products ofω3 andω6 20-and 22-carbon essential fatty
acids (FAs) that are formed enzymatically through “cyclooxygenases”. Prostaglandin …
acids (FAs) that are formed enzymatically through “cyclooxygenases”. Prostaglandin …
Thematic Review Series: proteomics. An integrated omics analysis of eicosanoid biology1 [S]
MW Buczynski, DS Dumlao, EA Dennis - Journal of lipid research, 2009 - ASBMB
Eicosanoids have been implicated in a vast number of devastating inflammatory conditions,
including arthritis, atherosclerosis, pain, and cancer. Currently, over a hundred different …
including arthritis, atherosclerosis, pain, and cancer. Currently, over a hundred different …
Prostaglandins and sleep–wake regulation
Y Urade, O Hayaishi - Sleep Disorders, 2008 - taylorfrancis.com
In the past 10 years, sleep science has developed remarkably owing to the development of
various types of molecular biological techniques. For example, a sleep center in the …
various types of molecular biological techniques. For example, a sleep center in the …
Recent advances in SN-38 drug delivery system
J Yang, L Jia, Z He, Y Wang - International Journal of Pharmaceutics, 2023 - Elsevier
DNA topoisomerase I plays a key role in lubricating the wheels of DNA replication or RNA
transcription through breaking and reconnecting DNA single-strand. It is widely known that …
transcription through breaking and reconnecting DNA single-strand. It is widely known that …
[HTML][HTML] Prostaglandin D2 inhibits wound-induced hair follicle neogenesis through the receptor, Gpr44
AM Nelson, DE Loy, JA Lawson, AS Katseff… - Journal of Investigative …, 2013 - Elsevier
Prostaglandins (PGs) are key inflammatory mediators involved in wound healing and
regulating hair growth; however, their role in skin regeneration after injury is unknown. Using …
regulating hair growth; however, their role in skin regeneration after injury is unknown. Using …
Structural dynamics and folding of β-lactoglobulin probed by heteronuclear NMR
K Sakurai, T Konuma, M Yagi, Y Goto - Biochimica et Biophysica Acta (BBA …, 2009 - Elsevier
Bovine β-lactoglobulin (βLG) has been one of the most extensively studied proteins in the
history of protein science mainly because its abundance in cow's milk makes it readily …
history of protein science mainly because its abundance in cow's milk makes it readily …
Biochemical and Structural Characteristics, Gene Regulation, Physiological, Pathological and Clinical Features of Lipocalin-Type Prostaglandin D2 Synthase as a …
Y Urade - Frontiers in Physiology, 2021 - frontiersin.org
Lipocalin-type prostaglandin (PG) D2 synthase (L-PGDS) catalyzes the isomerization of
PGH2, a common precursor of the two series of PGs, to produce PGD2. PGD2 stimulates …
PGH2, a common precursor of the two series of PGs, to produce PGD2. PGD2 stimulates …
Structure, functions, and implications of selected lipocalins in human disease
P Chandrasekaran, S Weiskirchen… - International Journal of …, 2024 - mdpi.com
The lipocalin proteins are a large family of small extracellular proteins that demonstrate
significant heterogeneity in sequence similarity and have highly conserved crystal …
significant heterogeneity in sequence similarity and have highly conserved crystal …
Lipocalin-type prostaglandin D synthase protects against oxidative stress-induced neuronal cell death
A Fukuhara, M Yamada, K Fujimori… - Biochemical …, 2012 - portlandpress.com
L-PGDS [lipocalin-type PGD (prostaglandin D) synthase] is a dual-functional protein, acting
as a PGD2-producing enzyme and a lipid transporter. L-PGDS is a member of the lipocalin …
as a PGD2-producing enzyme and a lipid transporter. L-PGDS is a member of the lipocalin …
Structure‐function analysis of human l‐prostaglandin D synthase bound with fatty acid molecules
Y Zhou, N Shaw, Y Li, Y Zhao, R Zhang… - The FASEB …, 2010 - Wiley Online Library
Human prostaglandin D synthase (L‐PGDS) is a lipocalin‐type enzyme involved in the
metabolism of arachidonic acid and plays a key role in the regulation of sleep, allergy, pain …
metabolism of arachidonic acid and plays a key role in the regulation of sleep, allergy, pain …