Prostanoids are cyclic, oxygenated products ofω3 andω6 20-and 22-carbon essential fatty
acids (FAs) that are formed enzymatically through “cyclooxygenases”. Prostaglandin …

Eicosanoids have been implicated in a vast number of devastating inflammatory conditions,
including arthritis, atherosclerosis, pain, and cancer. Currently, over a hundred different …

In the past 10 years, sleep science has developed remarkably owing to the development of
various types of molecular biological techniques. For example, a sleep center in the …

DNA topoisomerase I plays a key role in lubricating the wheels of DNA replication or RNA
transcription through breaking and reconnecting DNA single-strand. It is widely known that …

Prostaglandins (PGs) are key inflammatory mediators involved in wound healing and
regulating hair growth; however, their role in skin regeneration after injury is unknown. Using …

Bovine β-lactoglobulin (βLG) has been one of the most extensively studied proteins in the
history of protein science mainly because its abundance in cow's milk makes it readily …

Lipocalin-type prostaglandin (PG) D2 synthase (L-PGDS) catalyzes the isomerization of
PGH2, a common precursor of the two series of PGs, to produce PGD2. PGD2 stimulates …

The lipocalin proteins are a large family of small extracellular proteins that demonstrate
significant heterogeneity in sequence similarity and have highly conserved crystal …

L-PGDS [lipocalin-type PGD (prostaglandin D) synthase] is a dual-functional protein, acting
as a PGD2-producing enzyme and a lipid transporter. L-PGDS is a member of the lipocalin …

Human prostaglandin D synthase (L‐PGDS) is a lipocalin‐type enzyme involved in the
metabolism of arachidonic acid and plays a key role in the regulation of sleep, allergy, pain …