The reported incidence of eclampsia is 1.6 to 10 per 10,000 deliveries in developed
countries, whereas it is 50 to 151 per 10,000 deliveries in developing countries. In addition …

The kainic acid model of temporal lobe epilepsy has greatly contributed to the
understanding of the molecular, cellular and pharmacological mechanisms underlying …

The blood-brain barrier is dysfunctional in epilepsy, thereby contributing to seizure genesis
and resistance to antiseizure drugs. Previously, several groups reported that seizures …

Over the last 15 years, attention has been focused on dysfunction of the cerebral vasculature
and inflammation as important players in epileptogenic processes, with a specific emphasis …

The term neurovascular unit (NVU) describes the structural and functional liaison between
specialized brain endothelium, glial and mural cells, and neurons. Within the NVU, the blood …

Purpose: Previous studies have shown that inhibition of the mammalian target of rapamycin
(mTOR) pathway with rapamycin prevents epileptogenesis after pharmacologically induced …

Eclampsia, defined as unexplained seizure in a woman with preeclampsia, is a life-
threatening complication of pregnancy with unclear etiology. Magnesium sulfate (MgSO4) is …

MicroRNA (miRNA) is a class of small non-coding RNA which regulates post-transcriptional
gene expression by repressing and thereby fine-tuning protein production, mainly via …

Epilepsy is one of the most common serious chronic brain disorders, affecting up to 70
million people worldwide. Vascular disruption, including blood–brain barrier impairment and …

Matrix metalloproteinase 9 is a proteolytic enzyme which is recently one of the more often
studied biomarkers. Its possible use as a biomarker of neuronal damage in stroke, heart …