The neuromuscular junction in health and disease: molecular mechanisms governing synaptic formation and homeostasis
PM Rodríguez Cruz, J Cossins, D Beeson… - Frontiers in molecular …, 2020 - frontiersin.org
The neuromuscular junction (NMJ) is a highly specialized synapse between a motor neuron
nerve terminal and its muscle fiber that are responsible for converting electrical impulses …
nerve terminal and its muscle fiber that are responsible for converting electrical impulses …
Neuromuscular junction formation, aging, and disorders
Synapses, the fundamental unit in neuronal circuits, are critical for learning and memory,
perception, thinking, and reaction. The neuromuscular junction (NMJ) is a synapse formed …
perception, thinking, and reaction. The neuromuscular junction (NMJ) is a synapse formed …
[HTML][HTML] Mechanisms regulating neuromuscular junction development and function and causes of muscle wasting
LA Tintignac, HR Brenner… - Physiological …, 2015 - journals.physiology.org
The neuromuscular junction is the chemical synapse between motor neurons and skeletal
muscle fibers. It is designed to reliably convert the action potential from the presynaptic …
muscle fibers. It is designed to reliably convert the action potential from the presynaptic …
Cellular and molecular anatomy of the human neuromuscular junction
RA Jones, C Harrison, SL Eaton, ML Hurtado… - Cell reports, 2017 - cell.com
The neuromuscular junction (NMJ) plays a fundamental role in transferring information from
lower motor neuron to skeletal muscle to generate movement. It is also an experimentally …
lower motor neuron to skeletal muscle to generate movement. It is also an experimentally …
FUS-mediated regulation of acetylcholine receptor transcription at neuromuscular junctions is compromised in amyotrophic lateral sclerosis
G Picchiarelli, M Demestre, A Zuko, M Been… - Nature …, 2019 - nature.com
Neuromuscular junction (NMJ) disruption is an early pathogenic event in amyotrophic lateral
sclerosis (ALS). Yet, direct links between NMJ pathways and ALS-associated genes such as …
sclerosis (ALS). Yet, direct links between NMJ pathways and ALS-associated genes such as …
The neuromuscular junction: roles in aging and neuromuscular disease
SR Iyer, SB Shah, RM Lovering - International journal of molecular …, 2021 - mdpi.com
The neuromuscular junction (NMJ) is a specialized synapse that bridges the motor neuron
and the skeletal muscle fiber and is crucial for conversion of electrical impulses originating …
and the skeletal muscle fiber and is crucial for conversion of electrical impulses originating …
The Hippo pathway effector YAP is a critical regulator of skeletal muscle fibre size
The Yes-associated protein (YAP) is a core effector of the Hippo pathway, which regulates
proliferation and apoptosis in organ development. YAP function has been extensively …
proliferation and apoptosis in organ development. YAP function has been extensively …
A compartmentalized microfluidic neuromuscular co-culture system reveals spatial aspects of GDNF functions
EE Zahavi, A Ionescu, S Gluska… - Journal of cell …, 2015 - journals.biologists.com
Bidirectional molecular communication between the motoneuron and the muscle is vital for
neuromuscular junction (NMJ) formation and maintenance. The molecular mechanisms …
neuromuscular junction (NMJ) formation and maintenance. The molecular mechanisms …
The role of oxidative stress in degeneration of the neuromuscular junction in amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is characterized by the progressive loss of motoneurons
and degradation of the neuromuscular junctions (NMJ). Consistent with the dying-back …
and degradation of the neuromuscular junctions (NMJ). Consistent with the dying-back …
LRP4 is critical for neuromuscular junction maintenance
A Barik, Y Lu, A Sathyamurthy, A Bowman… - Journal of …, 2014 - Soc Neuroscience
The neuromuscular junction (NMJ) is a synapse between motor neurons and skeletal
muscle fibers, and is critical for control of muscle contraction. Its formation requires neuronal …
muscle fibers, and is critical for control of muscle contraction. Its formation requires neuronal …