Neuroinflammation, particularly in the dorsolateral prefrontal cortex, is well-established in a
subset of people with schizophrenia, with significant increases in inflammatory markers …

Cytokines are one of the most important components of the immune system. They
orchestrate the brain's response to infectious and other exogenous insults and are crucial …

The mortality rate of patients with schizophrenia is high, and life expectancy is shorter by 10
to 20 years. Metabolic abnormalities including type 2 diabetes mellitus (T2DM) are among …

Abstract Objective Interleukin 6 (IL-6) levels are commonly elevated in patients with
depression and psychosis and in people who are at risk of developing these disorders. A …

A high level of Interleukin-1beta (IL1B), a key mediator of inflammation, is expressed in the
brain, particularly in the hippocampus, which plays a pivotal role in memory and mood …

Objectives NFKB1 was associated with treatment-refractory schizophrenia (SZ) and
response to antipsychotics; however, the underlying mechanisms through which NFKB1 …

Background. Kawasaki disease (KD) is a systemic form of self‐limited vasculitis in children
less than five years old, and the main complication is coronary artery injury. However, the …

Neurocognitive difficulties are highly prevalent among people with schizophrenia and have
been linked to increased inflammation, as well as dysfunction and disability. Poor …

Cytokines are among the important effectors and messenger molecules for restoring the
homeostasis tissue after an inflammatory response. The association between IL-6 and IL-10 …

Psychotic and mood disorders are discussed as part of the same continuum. The potential
role of immune dysregulation in defining their clinical presentations, however, remains …