Over the past decade, research using virtual reality and serious game-based instruments for
assessing spatial navigation and spatial memory in at-risk and AD populations has risen …

Wearable digital technologies capable of measuring everyday behaviors could improve the
early detection of dementia‐causing diseases. We conducted two systematic reviews …

Background & aims Unhealthy lifestyles, such as chronic consumption of a Western Diet
(WD), have been associated with increased systemic inflammation and oxidative stress …

Aging results in less detailed memories, reflecting reduced fidelity of remembered compared
to real-world representations. We tested whether poorer representational fidelity across …

Cognitive tests sensitive to the integrity of the medial temporal lobe (MTL), such as
mnemonic discrimination of perceptually similar stimuli, may be useful early markers of risk …

Decreased fidelity of mnemonic representations plays a critical role in age-related episodic
memory deficits, yet the brain mechanisms underlying such reductions remain unclear …

Physical boundaries in our environment have been observed to define separate events in
episodic memory. To date, however, there is little evidence that the spatial properties of …

Spatial navigation abilities are frequently impaired in neurological disorders and they also
decline with normal aging. Researchers and clinicians therefore need valid and easy-to-use …

Background and purpose How the APOE genotype can differentially affect cortical and
subcortical memory structures in biomarker‐confirmed early‐onset (EOAD) and late‐onset …

Identifying individuals with incipient Alzheimer's disease (AD) are critical for early and
targeted intervention before the dementia develops as AD progresses. Recently, emerging …