Synthetic approaches and pharmacological activity of 1, 3, 4-oxadiazoles: a review of the literature from 2000–2012

CS De Oliveira, BF Lira, JM Barbosa-Filho… - Molecules, 2012 - mdpi.com
Molecules | Free Full-Text | Synthetic Approaches and Pharmacological Activity of 1,3,4-Oxadiazoles:
A Review of the Literature from 2000–2012 Next Article in Journal Chemical Composition of …

A review exploring therapeutic worth of 1, 3, 4-oxadiazole tailored compounds

G Verma, MF Khan, W Akhtar, MM Alam… - Mini Reviews in …, 2019 - ingentaconnect.com
1, 3, 4-Oxadiazole, a five-membered aromatic ring can be seen in a number of synthetic
molecules. The peculiar structural feature of 1, 3, 4-oxadiazole ring with pyridine type of …

Synthesis of Novel N-Acylhydrazones and Their CN/NN Bond Conformational Characterization by NMR Spectroscopy

R Munir, N Javid, M Zia-ur-Rehman, M Zaheer… - Molecules, 2021 - mdpi.com
In this article, a synthesis of N'-(benzylidene)-2-(6-methyl-1 H-pyrazolo [3, 4-b] quinolin-1-yl)
acetohydrazides and their structural interpretation by NMR experiments is described in an …

Anticancer profile and anti-inflammatory effect of new N-(2-((4-(1, 3-diphenyl-1H-pyrazol-4-yl) pyridine sulfonamide derivatives

MS Abdel-Maksoud, RM Hassan, AAS El-Azzouny… - Bioorganic …, 2021 - Elsevier
A new series of N-(2-((4-(1, 3-diphenyl-1H-pyrazol-4-yl) pyridine sulfonamide derivatives
11a-o were designed and synthesized based on our previous works. The new series was …

Aminoguanidine hydrazones (AGH's) as modulators of norfloxacin resistance in Staphylococcus aureus that overexpress NorA efflux pump

N Dantas, TM de Aquino, JX de Araújo-Júnior… - Chemico-biological …, 2018 - Elsevier
One of the promising fields for improving the effectiveness of antimicrobial agents is their
combination with efflux pump inhibitors (EPIs), which besides expanding the use of existing …

Design, synthesis, and antitumor activity of novel 5-pyridyl-1, 3, 4-oxadiazole derivatives against the breast cancer cell line MCF-7

NA Khalil, AM Kamal, SH Emam - Biological and Pharmaceutical …, 2015 - jstage.jst.go.jp
Design, Synthesis, and Antitumor Activity of Novel 5-Pyridyl-1,3,4-oxadiazole Derivatives
against the Breast Cancer Cell Line MCF-7 Toggle navigation J-STAGE home 資料・記事を探す …

Synthesis and antifungal activity of new hybrids pyrimido [4, 5-d] pyridazinone-N-acylhydrazones

AMF Rozada, FAV Rodrigues-Vendramini… - Bioorganic & Medicinal …, 2020 - Elsevier
Paracoccidioidomycosis is an endemic mycosis in Latin America for which there is a high
mortality rate and limited treatment options. There are no specific drugs to treat the systemic …

K 2 CO 3-mediated, direct C–H bond selenation and thiolation of 1, 3, 4-oxadiazoles in the absence of metal catalyst: An eco-friendly approach

J Rafique, S Saba, AR Rosário, G Zeni, AL Braga - RSC Advances, 2014 - pubs.rsc.org
An eco-friendly, straightforward and high-yielding methodology for the synthesis of
chalcogenyl oxadiazoles via the K2CO3-promoted direct C–H bond chalcogenation of 2 …

Synthesis of some novel heterocylic compounds derived from 2-[3-(4-chlorophenyl)-5-(4-methoxybenzyl)-4H-1, 2, 4-triazol-4-yl] acetohydrazide and investigation of …

O Bekircan, S Ülker, E Menteşe - Journal of enzyme inhibition and …, 2015 - Taylor & Francis
Abstract In the present study, 2-[3-(4-chlorophenyl)-5-(4-methoxybenzyl)-4H-1, 2, 4-triazol-4-
yl] acetohydrazide (1) was used as starting compound for the synthesis of 2-{[3-(4 …

Synthesis of New 2,5-Di-substituted 1,3,4-Oxadiazoles Bearing 2,6-Di-tert-butylphenol Moieties and Evaluation of Their Antioxidant Activity

RM Shakir, A Ariffin, MA Abdulla - molecules, 2014 - mdpi.com
Eleven new 2, 6-di-tert-butyl-4-(5-aryl-1, 3, 4-oxadiazol-2-yl) phenols 5a–k were synthesized
by reacting aryl hydrazides with 3, 5-di-tert butyl 4-hydroxybenzoic acid in the presence of …