Neisseria gonorrhoeae is the second most common bacterial sexually transmitted infection
in the world after Chlamydia trachomatis. The pathogen has developed resistance to every …

Introduction Several nucleic acid amplification tests (NAATs), mostly PCRs, to detect
antimicrobial resistance (AMR) determinants and predict AMR in Neisseria gonorrhoeae are …

Antimicrobial-resistant Neisseria gonorrhoeae infections are a threat to public health. Novel
strategies for combating such resistance include the development of molecular assays to …

Background Resistance to extended-spectrum cephalosporins (ESCs) has become a public
health concern with the spread of Neisseria gonorrhoeae and increasing antimicrobial …

Treatment regimens for gonorrhea have limited efficacy worldwide due to the rapid spread of
antimicrobial resistance. Cefixime (CFM) is currently not recommended as a first-line …

Cephalosporin resistance in Neisseria gonorrhoeae has severely compromised the efficacy
of World Health Organization (WHO)-recommended therapies. This study aimed to …

Antimicrobial resistance in N. gonorrhoeae is increasing globally, and ceftriaxone is the
recommended treatment for empirical therapy in most settings. Developing molecular …

The continuous rise of antimicrobial resistance (AMR) is a serious concern as it endangers
the effectiveness of healthcare interventions that rely on antibiotics in the long run. The …

The emerging cephalosporin-resistant Neisseria gonorrhoeae poses an urgent threat to the
continued efficacy of the last-line monotherapy for gonorrhea. Consequently, high …

Objectives To investigate the gene mutations associated with ceftriaxone (CRO) resistance
among gonococcal isolates, and to determine the effects of the mutated genes on CRO …