bitacora: A comprehensive tool for the identification and annotation of gene families in genome assemblies

J Vizueta, A Sánchez‐Gracia, J Rozas - 2020 - Wiley Online Library
Gene annotation is a critical bottleneck in genomic research, especially for the
comprehensive study of very large gene families in the genomes of nonmodel organisms …

The genomic architecture of the passerine MHC region: High repeat content and contrasting evolutionary histories of single copy and tandemly duplicated MHC genes

H Westerdahl, S Mellinger, H Sigeman… - Molecular Ecology …, 2022 - Wiley Online Library
The major histocompatibility complex (MHC) is of central importance to the immune system,
and an optimal MHC diversity is believed to maximize pathogen elimination. Birds show …

Dosage sensitivity and exon shuffling shape the landscape of polymorphic duplicates in Drosophila and humans

D Zhang, L Leng, C Chen, J Huang, Y Zhang… - Nature Ecology & …, 2022 - nature.com
Despite polymorphic duplicate genes' importance for the early stages of duplicate gene
evolution, they are less studied than old gene duplicates. Two essential questions thus …

Paralog transcriptional differentiation in the D. melanogaster-specific gene family Sdic across populations and spermatogenesis stages

BD Clifton, I Hariyani, A Kimura, F Luo… - Communications …, 2023 - nature.com
How recently originated gene copies become stable genomic components remains
uncertain as high sequence similarity of young duplicates precludes their functional …

DNA transposons mediate duplications via transposition-independent and-dependent mechanisms in metazoans

S Tan, H Ma, J Wang, M Wang, M Wang, H Yin… - Nature …, 2021 - nature.com
Despite long being considered as “junk”, transposable elements (TEs) are now accepted as
catalysts of evolution. One example is Mutator-like elements (MULEs, one type of terminal …

The chromosome‐scale assembly of the Canary Islands endemic spider Dysdera silvatica (Arachnida, Araneae) sheds light on the origin and genome structure of …

P Escuer, VA Pisarenco… - Molecular Ecology …, 2022 - Wiley Online Library
Here, we present the chromosome‐level genome assembly of Dysdera silvatica Schmidt,
1981, a nocturnal ground‐dwelling spider endemic from the Canary Islands. The genus …

Reconstructing gene gains and losses with BadiRate

P Librado, J Rozas - Environmental Microbial Evolution: Methods and …, 2022 - Springer
Estimating gene gain and losses is paramount to understand the molecular mechanisms
underlying adaptive evolution. Despite the advent of high-throughput sequencing, such …

GALEON: a comprehensive bioinformatic tool to analyse and visualize gene clusters in complete genomes

VA Pisarenco, J Vizueta, J Rozas - Bioinformatics, 2024 - academic.oup.com
Motivation Gene clusters, defined as a set of genes encoding functionally related proteins,
are abundant in eukaryotic genomes. Despite the increasing availability of chromosome …

Gnawing pressure led to the expansion of JAZ genes in angiosperms

B Zhang, H Zheng, H Wu, K Yan, P Xia… - International Journal of …, 2023 - Elsevier
A long-standing problem in evolutionary biology is why some populations differentiate into
many species while the majority do not. Angiosperms is an excellent group for investigating …

Genome mining and sequence analysis of chemosensory soluble proteins in arthropods

J Vizueta, P Escuer, A Sánchez-Gracia, J Rozas - Methods in enzymology, 2020 - Elsevier
Identifying protein-coding genes from genome and transcriptome data is the first and one of
the most important steps towards their comprehensive study. This chapter introduces both …