[HTML][HTML] The potential of using E. coli as an indicator for the surveillance of antimicrobial resistance (AMR) in the environment
Highlights•There is an urgent need for environmental Antimicrobial resistance (AMR)
monitoring.•E. coli are part of established human and livestock AMR surveillance …
monitoring.•E. coli are part of established human and livestock AMR surveillance …
[HTML][HTML] How do interactions between mobile genetic elements affect horizontal gene transfer?
T Horne, VT Orr, JPJ Hall - Current Opinion in Microbiology, 2023 - Elsevier
Highlights•Collaboration and conflict between MGEs can promote and inhibit HGT•Many
genome defences are MGE-encoded, serving MGE interests and changing frequently•The …
genome defences are MGE-encoded, serving MGE interests and changing frequently•The …
[HTML][HTML] Assessment of global health risk of antibiotic resistance genes
Z Zhang, Q Zhang, T Wang, N Xu, T Lu, W Hong… - Nature …, 2022 - nature.com
Antibiotic resistance genes (ARGs) have accelerated microbial threats to human health in
the last decade. Many genes can confer resistance, but evaluating the relative health risks of …
the last decade. Many genes can confer resistance, but evaluating the relative health risks of …
Role of mobile genetic elements in the global dissemination of the carbapenem resistance gene blaNDM
The mobile resistance gene bla NDM encodes the NDM enzyme which hydrolyses
carbapenems, a class of antibiotics used to treat some of the most severe bacterial …
carbapenems, a class of antibiotics used to treat some of the most severe bacterial …
A role for ColV plasmids in the evolution of pathogenic Escherichia coli ST58
CJ Reid, ML Cummins, S Börjesson… - Nature …, 2022 - nature.com
Escherichia coli ST58 has recently emerged as a globally disseminated uropathogen that
often progresses to sepsis. Unlike most pandemic extra-intestinal pathogenic E. coli …
often progresses to sepsis. Unlike most pandemic extra-intestinal pathogenic E. coli …
Comparison of R9. 4.1/Kit10 and R10/Kit12 Oxford Nanopore flowcells and chemistries in bacterial genome reconstruction
ND Sanderson, N Kapel, G Rodger… - Microbial …, 2023 - microbiologyresearch.org
Complete, accurate, cost-effective, and high-throughput reconstruction of bacterial genomes
for large-scale genomic epidemiological studies is currently only possible with hybrid …
for large-scale genomic epidemiological studies is currently only possible with hybrid …
Role of horizontal gene transfer in the dissemination of antimicrobial resistance in food animal production
PG Vinayamohan, AJ Pellissery… - Current Opinion in Food …, 2022 - Elsevier
Highlights•Microorganisms acquires antimicrobial resistance genes via horizontal gene
transfer.•Mobile genetic elements disseminate antimicrobial resistance genes in the food …
transfer.•Mobile genetic elements disseminate antimicrobial resistance genes in the food …
Ten-year longitudinal molecular epidemiology study of Escherichia coli and Klebsiella species bloodstream infections in Oxfordshire, UK
S Lipworth, KD Vihta, K Chau, L Barker, S George… - Genome Medicine, 2021 - Springer
Abstract Background The incidence of Gram-negative bloodstream infections (BSIs),
predominantly caused by Escherichia coli and Klebsiella species, continues to increase; …
predominantly caused by Escherichia coli and Klebsiella species, continues to increase; …
Aeromonas spp. from hospital sewage act as a reservoir of genes resistant to last-line antibiotics
Y Wu, N Dong, C Cai, Y Zeng, J Lu, C Liu… - Drug Resistance …, 2023 - Elsevier
Background Aeromonas species are opportunistic pathogens distributed widely in the
ecosystem. They are known to be capable of acquiring antibiotic resistance genes, including …
ecosystem. They are known to be capable of acquiring antibiotic resistance genes, including …
[HTML][HTML] Systematic review of wastewater surveillance of antimicrobial resistance in human populations
KK Chau, L Barker, EP Budgell, KD Vihta, N Sims… - Environment …, 2022 - Elsevier
Objectives We systematically reviewed studies using wastewater for AMR surveillance in
human populations, to determine:(i) evidence of concordance between wastewater-human …
human populations, to determine:(i) evidence of concordance between wastewater-human …