Identification and prioritization of environmental organic pollutants: from an analytical and toxicological perspective

T Ruan, P Li, H Wang, T Li, G Jiang - Chemical Reviews, 2023 - ACS Publications
Exposure to environmental organic pollutants has triggered significant ecological impacts
and adverse health outcomes, which have been received substantial and increasing …

Understanding the combined effects of multiple stressors: A new perspective on a longstanding challenge

E Pirotta, L Thomas, DP Costa, AJ Hall… - Science of the Total …, 2022 - Elsevier
Wildlife populations and their habitats are exposed to an expanding diversity and intensity of
stressors caused by human activities, within the broader context of natural processes and …

A quantile-based g-computation approach to addressing the effects of exposure mixtures

AP Keil, JP Buckley, KM O'Brien… - Environmental …, 2020 - ehp.niehs.nih.gov
Background: Exposure mixtures frequently occur in data across many domains, particularly
in the fields of environmental and nutritional epidemiology. Various strategies have arisen to …

Statistical software for analyzing the health effects of multiple concurrent exposures via Bayesian kernel machine regression

JF Bobb, B Claus Henn, L Valeri, BA Coull - Environmental Health, 2018 - Springer
Background Estimating the health effects of multi-pollutant mixtures is of increasing interest
in environmental epidemiology. Recently, a new approach for estimating the health effects of …

[HTML][HTML] Environmental chemicals and breast cancer: An updated review of epidemiological literature informed by biological mechanisms

KM Rodgers, JO Udesky, RA Rudel, JG Brody - Environmental research, 2018 - Elsevier
Background Many common environmental chemicals are mammary gland carcinogens in
animal studies, activate relevant hormonal pathways, or enhance mammary gland …

Bayesian kernel machine regression for estimating the health effects of multi-pollutant mixtures

JF Bobb, L Valeri, B Claus Henn, DC Christiani… - …, 2015 - academic.oup.com
Because humans are invariably exposed to complex chemical mixtures, estimating the
health effects of multi-pollutant exposures is of critical concern in environmental …

Expanded target-chemical analysis reveals extensive mixed-organic-contaminant exposure in US streams

PM Bradley, CA Journey, KM Romanok… - … science & technology, 2017 - ACS Publications
Surface water from 38 streams nationwide was assessed using 14 target-organic methods
(719 compounds). Designed-bioactive anthropogenic contaminants (biocides …

What can epidemiological studies tell us about the impact of chemical mixtures on human health?

JM Braun, C Gennings, R Hauser… - Environmental health …, 2016 - ehp.niehs.nih.gov
Humans are exposed to a large number of environmental chemicals: Some of these may be
toxic, and many others have unknown or poorly characterized health effects. There is …

Perinatal and childhood exposure to cadmium, manganese, and metal mixtures and effects on cognition and behavior: a review of recent literature

AP Sanders, B Claus Henn, RO Wright - Current environmental health …, 2015 - Springer
Abstract Lead (Pb) and mercury (Hg) neurotoxicity is well established. In recent years, a
growing body of evidence suggests that environmental exposure to other metals including …

Statistical methodology in studies of prenatal exposure to mixtures of endocrine-disrupting chemicals: a review of existing approaches and new alternatives

N Lazarevic, AG Barnett, PD Sly… - Environmental health …, 2019 - ehp.niehs.nih.gov
Background: Prenatal exposures to endocrine-disrupting chemicals (EDCs) during critical
developmental windows have been implicated in the etiologies of a wide array of adverse …