Weifuchun suppresses the malignancy of gastric cancer cells by targeting KPNA2 through miR-26a-5p-mediated destabilization and the deactivation of the MAPK …

L Ma, X Hu, W Zhang, D Qi, L Chen, M Yin - Journal of Ethnopharmacology, 2024 - Elsevier
Ethnopharmacological relevance Weifuchun (WFC) is a Traditional Chinese Medicine
commonly used for treating atrophic gastritis and intestinal metaplasia. Till date, its antitumor …

[HTML][HTML] A gap analysis of UK biobank publications reveals SNPs associated with intrinsic subtypes of breast cancer

L van den Driest, P Kelly, A Marshall… - Computational and …, 2024 - Elsevier
Breast cancer is a multifaceted disease and a leading cause of cancer morbidity and
mortality in females across the globe. In 2020 alone, 2.3 million women were diagnosed and …

Proteomic profiling improves prognostic risk stratification of the Sarculator nomogram in soft tissue sarcomas of the extremities and trunk wall

M Chadha, S Iadecola, A Jenks, V Pankova… - Cancer …, 2024 - Wiley Online Library
Background High‐risk soft tissue sarcomas of the extremities and trunk wall (eSTS), as
defined by the Sarculator nomogram, are more likely to benefit from (neo) adjuvant …

Oxidative stress mediates nucleocytoplasmic shuttling of KPNA2 via AKT1‐CDK1 axis‐regulated S62 phosphorylation

JX Huang, CI Wang, CY Kuo, TW Chang… - FASEB …, 2024 - pmc.ncbi.nlm.nih.gov
Abstract Karyopherin α 2 (KPNA2, importin α1), a transport factor shuttling between the
nuclear and cytoplasmic compartments, is involved in the nuclear import of proteins and …

Recounting the untold stories of breast cancer patient experiences: lessons learned from a patient–public involvement and engagement storytelling event

MR Cunningham, NJW Rattray… - … Journal of Pharmacy …, 2024 - academic.oup.com
Objectives Breast cancer remains a prevalent disease in women worldwide. Though
advancements in breast cancer care have improved patient survival, a breast cancer …

Proteomic characterisation of Sarculator nomogram-defined risk groups in soft tissue sarcomas of the extremities and trunk wall

M Chadha, S Iadecola, A Jenks, J Burns, A Arthur… - bioRxiv, 2023 - biorxiv.org
Background High-risk soft tissue sarcomas of the extremities and trunk wall (eSTS), as
defined by the Sarculator nomogram, are more likely to benefit from (neo) adjuvant …

[引用][C] 核转运蛋白α2 通过ERK 信号通路调控乳腺癌细胞生物学行为的研究

冉冉, 刘蔡杨, 王浩, 何幸, 寇玲娜 - 中国普通外科杂志, 2024