Sulfonamides with heterocyclic periphery as antiviral agents

MY Moskalik - Molecules, 2022 - mdpi.com
Sulfonamides are the basic motifs for a whole generation of drugs from a large group of
antibiotics. Currently, research in the field of the new sulfonamide synthesis has received a …

Targeting the Annexin A1-FPR2/ALX pathway for host-directed therapy in dengue disease

VV Costa, MA Sugimoto, J Hubner, CS Bonilha… - Elife, 2022 - elifesciences.org
Host immune responses contribute to dengue's pathogenesis and severity, yet the possibility
that failure in endogenous inflammation resolution pathways could characterise the disease …

Inhibition of Tryptophan Catabolism Is Associated With Neuroprotection During Zika Virus Infection

FM Marim, DC Teixeira, CM Queiroz-Junior… - Frontiers in …, 2021 - frontiersin.org
Zika virus (ZIKV) is an arbovirus belonging to Flaviviridae family that emerged as a global
health threat due to its association with microcephaly and other severe neurological …

Discovery of a 2′-Fluoro, 2′-bromouridine phosphoramidate prodrug exhibiting anti-yellow fever virus activity in culture and in mice

JC LeCher, K Zandi, VV Costa, F Amblard, S Tao… - Microorganisms, 2022 - mdpi.com
Yellow fever virus (YFV) is a potentially lethal, zoonotic, blood-borne flavivirus transmitted to
humans and non-human primates by mosquitoes. Owing to multiple deadly epidemics, the …

[HTML][HTML] Human neural progenitor cell models to study the antiviral effects and neuroprotective potential of approved and investigational human cytomegalovirus …

M Trevisan, A Pianezzola, M Onorati, L Apolloni… - Antiviral Research, 2024 - Elsevier
Human cytomegalovirus (HCMV) is the viral leading cause of congenital defects in
newborns worldwide. Many aspects of congenital CMV (cCMV) infection, which currently …

Novel nucleoside analogues as effective antiviral agents for Zika virus infections

M Bassetto, CM Cima, M Basso, M Salerno… - Molecules, 2020 - mdpi.com
Previously considered a neglected flavivirus, Zika virus has recently emerged as a public
health concern due to its ability to spread rapidly and cause severe neurological disorders …

Exploration of novel hexahydropyrrolo [1, 2-e] imidazol-1-one derivatives as antiviral agents against ZIKV and USUV

R Chen, R Francese, N Wang, F Li, X Sun, B Xu… - European Journal of …, 2023 - Elsevier
Zika virus (ZIKV) and Usutu virus (USUV) are two emerging flaviviruses mostly transmitted
by mosquitos. ZIKV is associated with microcephaly in newborns and the less-known USUV …

Design, synthesis, and biological evaluation of novel 2′-methyl-2′-fluoro-6-methyl-7-alkynyl-7-deazapurine nucleoside analogs as anti-Zika virus agents

G Yao, J Yu, C Lin, Y Zhu, A Duan, M Li, J Yuan… - European Journal of …, 2022 - Elsevier
Zika virus (ZIKV) is a mosquito-borne flavivirus and outbreaks of ZIKV have been reported in
Africa, Americas and other parts of the world lately. The ZIKV epidemic has received …