Biomechanical and biological responses of periodontium in orthodontic tooth movement: up-date in a new decade

Y Li, Q Zhan, M Bao, J Yi, Y Li - International journal of oral science, 2021 - nature.com
Nowadays, orthodontic treatment has become increasingly popular. However, the biological
mechanisms of orthodontic tooth movement (OTM) have not been fully elucidated. We were …

Challenges of periodontal tissue engineering: increasing biomimicry through 3D printing and controlled dynamic environment

I Roato, B Masante, G Putame, D Massai, F Mussano - Nanomaterials, 2022 - mdpi.com
In recent years, tissue engineering studies have proposed several approaches to
regenerate periodontium based on the use of three-dimensional (3D) tissue scaffolds alone …

Expression of biological mediators during orthodontic tooth movement: A systematic review

L Vansant, MC De Llano-Pérula, A Verdonck… - Archives of Oral …, 2018 - Elsevier
Objectives The aim of the present systematic review was to offer a timeline of the events
taking place during orthodontic tooth movement (OTM). Materials and methods Electronic …

Functional role of mechanosensitive ion channel Piezo1 in human periodontal ligament cells

Y Jin, J Li, Y Wang, R Ye, X Feng… - The Angle …, 2015 - meridian.allenpress.com
Objective: To evaluate the function of Piezo1, an evolutionarily conserved mechanically
activated channel, in periodontal ligament (PDL) tissue homeostasis under compressive …

Drug-loadable calcium alginate hydrogel system for use in oral bone tissue repair

L Chen, R Shen, S Komasa, Y Xue, B Jin… - International Journal of …, 2017 - mdpi.com
This study developed a drug-loadable hydrogel system with high plasticity and favorable
biological properties to enhance oral bone tissue regeneration. Hydrogels of different …

Fluid flow-induced modulation of viability and osteodifferentiation of periodontal ligament stem cell spheroids-on-chip

A Mishra, R Kai, S Atkuru, Y Dai, F Piccinini… - Biomaterials …, 2023 - pubs.rsc.org
Developing physiologically relevant in vitro models for studying periodontitis is crucial for
understanding its pathogenesis and developing effective therapeutic strategies. In this study …

PTH/PTHrP in controlled release hydrogel enhances orthodontic tooth movement by regulating periodontal bone remodaling

W Lu, X Li, Y Yang, J Yi, L Xie… - Journal of Periodontal …, 2021 - Wiley Online Library
Objective This study aimed to evaluate the effects of local application of parathyroid
hormone (PTH) or parathyroid hormone‐related protein (PTHrP) on osteogenesis and …

CXCL5, CXCL8, and CXCL10 regulation by bacteria and mechanical forces in periodontium

B Rath-Deschner, S Memmert, A Damanaki… - Annals of Anatomy …, 2021 - Elsevier
Objective The aim of the present study was to evaluate the expressions of CXCL5, CXCL8,
and CXCL10 in periodontal cells and tissues in response to microbial signals and/or …

Periodontal cell mechanotransduction

SS Chukkapalli, TP Lele - Open Biology, 2018 - royalsocietypublishing.org
The periodontium is a structurally and functionally complex tissue that facilitates the
anchorage of teeth in jaws. The periodontium consists of various cell types including stem …

In vitro mechanical loading models for periodontal ligament cells: from two-dimensional to three-dimensional models

L Yang, Y Yang, S Wang, Y Li, Z Zhao - Archives of Oral Biology, 2015 - Elsevier
Periodontal ligament cells (PDLCs) respond to various mechanical stimuli, including
mastication and orthodontic force, and thereby play an important functional role. A number of …