The ability to rapidly identify immune cell subsets such as CD4 cells, which became possible
around the same time as the onset of the HIV/AIDS pandemic, was one of the greatest …

Background During the COVID-19 pandemic, men who have sex with men (MSM) in the
USA have reported similar or fewer sexual partners and reduced HIV testing and care …

Background: Lifetime costs of care and quality-of-life estimates for HIV-infected persons
depend on the disease stage at which these persons are diagnosed, enter care, and start …

HIV virulence, ie the time of progression to AIDS, varies greatly among patients. As for other
rapidly evolving pathogens of humans, it is difficult to know if this variance is controlled by …

Abstract (See the editorial commentary by Tossonian and Conway, on pages 10–12.)
Background. The benefits of antiretroviral therapy during early human immunodeficiency …

Objective: The potential for changing HIV-1 virulence has significant implications for the
AIDS epidemic, including changing HIV transmission rates, rapidity of disease progression …

Should emerging pathogens be unusually virulent? If so, why? Existing theories of virulence
evolution based on a tradeoff between high transmission rates and long infectious periods …

The plan for Ending the HIV (human immunodeficiency virus) Epidemic (EHE) in the United
States aims to reduce new infections by 75% by 2025 and by 90% by 2030. For EHE to be …

Approximately 1% of those infected with HIV-1 develop broad and potent serum cross-
neutralizing antibody activities. It is unknown whether or not the development of such …

HLA-restricted immune escape mutations that persist following HIV transmission could
gradually spread through the viral population, thereby compromising host antiviral immunity …