HIV-Associated neurocognitive disorder (HAND) is one of the major concerns since it
persists in 40% of this population. Nowadays, HAND neuropathogenesis is considered to be …

Type 2 diabetes is a disease with significant health consequences for the individual.
Currently, new mechanisms and therapeutic approaches that may affect this disease are …

Diabetic cardiomyopathy (DCM) is a common complication in patients with diabetes, and
ultimately leads to heart failure. Endoplasmic reticulum stress (ERS) induced by abnormal …

Vascular endothelial dysfunction (VED) is linked with the pathogenesis of obstructive sleep
apnea (OSA) comorbidities, such as cardiovascular disease. Astragaloside IV (As-IV) has …

Our previous studies uncovered the glucose-lowering properties of snow chrysanthemum
tea, however, the active ingredients and underlying mechanisms were yet to be uncovered …

Type 2 diabetes mellitus (T2DM) is a disease characterized by a prolonged hyperglycemic
condition caused by insulin resistance mechanisms in muscle and liver, reduced insulin …

Abstract Purpose Environmental pollutant Bisphenol A (BPA) strongly interacts with insulin
resistance, which leads to type 2 diabetes mellitus (T2DM). Uncontrolled glucose levels in …

Background: The existence of aberrant myocardial activity and function in the exclusion of
those other cardiovascular events, such as atherosclerosis, hypertension, and severe valve …

Objective Berberine (BBR) has emerged as a promising therapeutic agent for nonalcoholic
fatty liver disease (NAFLD). This study aims to elucidate the underlying molecular …

Oxidative and dicarbonyl stress, driven by excess accumulation of glycolytic intermediates in
cells that are highly permeable to glucose in the absence of effective insulin activity, appear …