Third-generation autologous chondrocyte implantation (cells cultured within collagen membrane) is superior to microfracture for focal chondral defects of the knee joint …
J Dhillon, AP Decilveo, MJ Kraeutler, JW Belk… - … : The Journal of …, 2022 - Elsevier
Purpose To systematically review randomized controlled trials to compare clinical outcomes
of microfracture (MFx) versus third-generation autologous chondrocyte implantation (ACI) for …
of microfracture (MFx) versus third-generation autologous chondrocyte implantation (ACI) for …
Hydrogel composite scaffolds achieve recruitment and chondrogenesis in cartilage tissue engineering applications
Background The regeneration and repair of articular cartilage remains a major challenge for
clinicians and scientists due to the poor intrinsic healing of this tissue. Since cartilage …
clinicians and scientists due to the poor intrinsic healing of this tissue. Since cartilage …
Integrins, cadherins and channels in cartilage mechanotransduction: perspectives for future regeneration strategies
MP Dieterle, A Husari, B Rolauffs… - Expert Reviews in …, 2021 - cambridge.org
Articular cartilage consists of hyaline cartilage, is a major constituent of the human
musculoskeletal system and has critical functions in frictionless joint movement and articular …
musculoskeletal system and has critical functions in frictionless joint movement and articular …
The current status of clinical trials on biologics for cartilage repair and osteoarthritis treatment: an analysis of ClinicalTrials. gov data
Z Zhang, L Schon - Cartilage, 2022 - journals.sagepub.com
Objective Biologics are increasingly used for cartilage repair and osteoarthritis (OA)
treatment. This study aimed to provide an overview of the clinical trials conducted on this …
treatment. This study aimed to provide an overview of the clinical trials conducted on this …
Cartilage tissue engineering in practice: preclinical trials, clinical applications, and prospects
Articular cartilage defects significantly compromise the quality of life in the global population.
Although many strategies are needed to repair articular cartilage, including microfracture …
Although many strategies are needed to repair articular cartilage, including microfracture …
Biological reconstruction of localized full-thickness cartilage defects of the knee: a systematic review of level 1 studies with a minimum follow-up of 5 years
P Angele, J Zellner, S Schroeter… - Cartilage, 2022 - journals.sagepub.com
Objective The objective of this study was to evaluate the best available mid-to long-term
evidence of surgical procedures for the treatment of localized full-thickness cartilage defects …
evidence of surgical procedures for the treatment of localized full-thickness cartilage defects …
[HTML][HTML] Patellar malalignment: A common disorder associated with knee pain
CC Wu - biomedical journal, 2023 - Elsevier
Pain-associated knee joint disorders are common in daily life. Practically, knee pain should
be divided into the origin from the isolated tibiofemoral (TF), isolated patellofemoral (PF) …
be divided into the origin from the isolated tibiofemoral (TF), isolated patellofemoral (PF) …
[HTML][HTML] Endogenus chondrocytes immobilized by G-CSF in nanoporous gels enable repair of critical-size osteochondral defects
S Tang, R Zhang, H Bai, R Shu, D Chen, L He… - Materials Today Bio, 2024 - Elsevier
Injured articular cartilage is a leading cause for osteoarthritis. We recently discovered that
endogenous stem/progenitor cells not only reside in the superficial zone of mouse articular …
endogenous stem/progenitor cells not only reside in the superficial zone of mouse articular …
Perspective in achieving stratified articular cartilage repair using zonal chondrocytes
Articular cartilage is composed of superficial, medial, and deep zones, which endow the
tissue with biphasic mechanical properties to withstand shearing force and compressional …
tissue with biphasic mechanical properties to withstand shearing force and compressional …
[HTML][HTML] Does progress in microfracture techniques necessarily translate into clinical effectiveness?
S Muthu, VK Viswanathan, M Sakthivel… - World Journal of …, 2024 - ncbi.nlm.nih.gov
BACKGROUND Multitudinous advancements have been made to the traditional
microfracture (MFx) technique, which have involved delivery of various acellular 2 nd …
microfracture (MFx) technique, which have involved delivery of various acellular 2 nd …