Cubosomes: the next generation of smart lipid nanoparticles?

HMG Barriga, MN Holme… - Angewandte Chemie …, 2019 - Wiley Online Library
Cubosomes are highly stable nanoparticles formed from the lipid cubic phase and stabilized
by a polymer based outer corona. Bicontinuous lipid cubic phases consist of a single lipid …

Cubosomes as an emerging platform for drug delivery: A review of the state of the art

MAS Abourehab, MJ Ansari, A Singh… - Journal of Materials …, 2022 - pubs.rsc.org
Lipid-based drug-delivery nanoparticles, including non-lamellar-type, mesophasic
nanostructured materials of lyotropic liquid crystals (LLCs), have been a topic of interest for …

Lipid vesicles: A versatile drug delivery platform for dermal and transdermal applications

IA Chacko, VM Ghate, L Dsouza, SA Lewis - Colloids and Surfaces B …, 2020 - Elsevier
Topical and transdermal application of active pharmaceutical ingredients to the skin is an
attractive strategy being explored by formulation scientists to treat disease conditions rather …

Recent trends, challenges and future outlook of transdermal drug delivery systems for rheumatoid arthritis therapy

M Qindeel, MH Ullah, N Ahmed - Journal of Controlled Release, 2020 - Elsevier
At present, several drug molecules have been used for the treatment of rheumatoid arthritis
(RA). However, the utilization of these compounds through the oral and parenteral route is …

Advances in lyotropic liquid crystal systems for skin drug delivery

AVP Silvestrini, AL Caron, J Viegas… - Expert Opinion on …, 2020 - Taylor & Francis
ABSTRACT Introduction Lyotropic liquid crystals (LLCs) are organized mesophases with
intermediate properties between liquids and solids. The LLC and its liquid crystalline …

Advances in the design of ph-sensitive cubosome liquid crystalline nanocarriers for drug delivery applications

O Mertins, PD Mathews, A Angelova - Nanomaterials, 2020 - mdpi.com
Nanostructure bicontinuous cubic phase self-assembled materials are receiving expanding
applications as biocompatible delivery systems in various therapeutic fields. The …

[HTML][HTML] Cubosomes-assisted transdermal delivery of doxorubicin and indocyanine green for chemo-photothermal combination therapy of melanoma

Z Chen, Q Huang, Y Song, X Feng, L Zeng, Z Liu… - Biomedicine & …, 2023 - Elsevier
Melanoma is a highly aggressive form of skin cancer with limited therapeutic options.
Chemo-photothermal combination therapy has demonstrated potential for effectively treating …

Recent advances in nanomaterials for dermal and transdermal applications

A Zoabi, E Touitou, K Margulis - Colloids and Interfaces, 2021 - mdpi.com
The stratum corneum, the most superficial layer of the skin, protects the body against
environmental hazards and presents a highly selective barrier for the passage of drugs and …

Formulation and evaluation of cubosomes drug delivery system for treatment of glaucoma: Ex-vivo permeation and in-vivo pharmacodynamic study

AE Eldeeb, S Salah, M Ghorab - Journal of Drug Delivery Science and …, 2019 - Elsevier
Glaucoma, a chronic disease of elevated intraocular pressure, is considered as the first
leading cause of blindness. Brimonidine tartrate (BRT), a hydrophilic drug with poor ocular …

Polymer nanotherapeutics to correct autoimmunity

T Su, X Feng, J Yang, W Xu, T Liu, M Zhang… - Journal of Controlled …, 2022 - Elsevier
The immune system maintains homeostasis and protects the body from pathogens, mutated
cells, and other harmful substances. When immune homeostasis is disrupted, excessive …