Biological and psychological markers of stress in humans: Focus on the Trier Social Stress Test

AP Allen, PJ Kennedy, JF Cryan, TG Dinan… - … & biobehavioral reviews, 2014 - Elsevier
Validated biological and psychological markers of acute stress in humans are an important
tool in translational research. The Trier Social Stress Test (TSST), involving public interview …

Sensitivity to the depressogenic effect of stress and HPA-axis reactivity in adolescence: a review of gender differences

AJ Oldehinkel, EMC Bouma - Neuroscience & Biobehavioral Reviews, 2011 - Elsevier
Adolescence is characterized by major biological, psychological, and social challenges, as
well as by an increase in depression rates. This review focuses on the association between …

Increased serotonin transporter gene (SERT) DNA methylation is associated with bullying victimization and blunted cortisol response to stress in childhood: a …

I Ouellet-Morin, CCY Wong, A Danese… - Psychological …, 2013 - cambridge.org
BackgroundChildhood adverse experiences are known to induce persistent changes in the
hypothalamic–pituitary–adrenal (HPA) axis reactivity to stress. However, the mechanisms by …

The serotonin transporter gene-linked polymorphic region (5-HTTLPR) and cortisol stress reactivity: a meta-analysis

R Miller, M Wankerl, T Stalder, C Kirschbaum… - Molecular …, 2013 - nature.com
Recent meta-analyses have stimulated an active debate on whether the serotonin
transporter gene-linked polymorphic region (5-HTTLPR) is associated with an elevated …

The TRacking Adolescents' Individual Lives Survey (TRAILS): design, current status, and selected findings

J Ormel, AJ Oldehinkel, J Sijtsema, F van Oort… - Journal of the American …, 2012 - Elsevier
OBJECTIVES: The objectives of this study were as follows: to present a concise overview of
the sample, outcomes, determinants, non-response and attrition of the ongoing TRacking …

DNA methylation profiles within the serotonin transporter gene moderate the association of 5-HTTLPR and cortisol stress reactivity

N Alexander, M Wankerl, J Hennig, R Miller… - Translational …, 2014 - nature.com
The serotonin transporter gene-linked polymorphic region (5-HTTLPR) has been implicated
in moderating vulnerability to stress-related psychopathology upon exposure to …

Neural mechanisms underlying 5-HTTLPR-related sensitivity to acute stress

EM Drabant, W Ramel, MD Edge… - American Journal of …, 2012 - Am Psychiatric Assoc
Objective: Many studies have shown that 5-HTTLPR genotype interacts with exposure to
stress in conferring risk for psychopathology. However, the specific neural mechanisms …

Toward an integration of cognitive and genetic models of risk for depression

BE Gibb, CG Beevers, JE McGeary - Cognition & emotion, 2013 - Taylor & Francis
There is growing interest in integrating cognitive and genetic models of depression risk. We
review two ways in which these models can be meaningfully integrated. First, information …

The serotonin transporter polymorphism (5-HTTLPR) and cortisol stress responsiveness: preliminary evidence for a modulating role for sleep quality

JH van Dalfsen, CR Markus - Stress, 2018 - Taylor & Francis
The short (S) allele of a functional polymorphism (5-HTTLPR) within the promoter region of
the serotonin transporter gene (SLC6A4) is found to predispose the risk for stress-related …

Diurnal cortisol rhythms in youth from risky families: Effects of cumulative risk exposure and variation in the serotonin transporter linked polymorphic region gene

CJ Willner, PA Morris, DC McCoy… - Development and …, 2014 - cambridge.org
Building on research on cumulative risk and psychopathology, this study examines how
cumulative risk exposure is associated with altered diurnal cortisol rhythms in an ethnically …