Overview of SARS-CoV-2 genome-encoded proteins
C Bai, Q Zhong, GF Gao - Science China Life Sciences, 2022 - Springer
Severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) has spread rapidly
throughout the world. SARS-CoV-2 is an enveloped, plus-stranded RNA virus with a single …
throughout the world. SARS-CoV-2 is an enveloped, plus-stranded RNA virus with a single …
[HTML][HTML] Recognition of the SARS-CoV-2 receptor binding domain by neutralizing antibodies
Immediately from the outset of the COVID-19 pandemic, researchers from diverse
biomedical and biological disciplines have united to study the novel pandemic virus, SARS …
biomedical and biological disciplines have united to study the novel pandemic virus, SARS …
SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies
Abstract The coronavirus disease 2019 (COVID-19) pandemic presents an urgent health
crisis. Human neutralizing antibodies that target the host ACE2 receptor-binding domain …
crisis. Human neutralizing antibodies that target the host ACE2 receptor-binding domain …
Antibody potency, effector function, and combinations in protection and therapy for SARS-CoV-2 infection in vivo
SARS-CoV-2, the causative agent of COVID-19, has been responsible for over 42 million
infections and 1 million deaths since its emergence in December 2019. There are few …
infections and 1 million deaths since its emergence in December 2019. There are few …
Neutralizing antibody therapeutics for COVID-19
AC Hurt, AK Wheatley - Viruses, 2021 - mdpi.com
The emergence of SARS-CoV-2 and subsequent COVID-19 pandemic has resulted in a
significant global public health burden, leading to an urgent need for effective therapeutic …
significant global public health burden, leading to an urgent need for effective therapeutic …
[HTML][HTML] Neutralizing antibodies targeting SARS-CoV-2 spike protein
S Xiaojie, L Yu, Y Guang, Q Min - Stem cell research, 2021 - Elsevier
SARS-CoV-2 causing the worldwide pandemic has changed people's life in multiple aspects
dramatically since it's first identified in Wuhan, China at the end of 2019. While the numbers …
dramatically since it's first identified in Wuhan, China at the end of 2019. While the numbers …
Mutation-induced changes in the receptor-binding interface of the SARS-CoV-2 Delta variant B. 1.617. 2 and implications for immune evasion
Following the initial surges of the Alpha (B. 1.1. 7) and the Beta (B. 1.351) variants, a more
infectious Delta variant (B. 1.617. 2) is now surging, further deepening the health crises …
infectious Delta variant (B. 1.617. 2) is now surging, further deepening the health crises …
Bi-paratopic and multivalent VH domains block ACE2 binding and neutralize SARS-CoV-2
CJ Bracken, SA Lim, P Solomon, NJ Rettko… - Nature chemical …, 2021 - nature.com
Neutralizing agents against SARS-CoV-2 are urgently needed for the treatment and
prophylaxis of COVID-19. Here, we present a strategy to rapidly identify and assemble …
prophylaxis of COVID-19. Here, we present a strategy to rapidly identify and assemble …
Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies
Neutralizing monoclonal antibodies (nAbs) to severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) represent promising candidates for clinical intervention against …
coronavirus 2 (SARS-CoV-2) represent promising candidates for clinical intervention against …
Sensitive detection of total anti-Spike antibodies and isotype switching in asymptomatic and symptomatic individuals with COVID-19
Early detection of infection is crucial to limit the spread of coronavirus disease 2019 (COVID-
19). Here we develop a flow cytometry-based assay to detect severe acute respiratory …
19). Here we develop a flow cytometry-based assay to detect severe acute respiratory …