Benzylisoquinoline alkaloid metabolism: a century of discovery and a brave new world
JM Hagel, PJ Facchini - Plant and Cell Physiology, 2013 - academic.oup.com
Benzylisoquinoline alkaloids (BIAs) are a structurally diverse group of plant specialized
metabolites with a long history of investigation. Although the ecophysiological functions of …
metabolites with a long history of investigation. Although the ecophysiological functions of …
[HTML][HTML] Benzylisoquinoline alkaloid biosynthesis in opium poppy
GAW Beaudoin, PJ Facchini - Planta, 2014 - Springer
Opium poppy (Papaver somniferum) is one of the world's oldest medicinal plants and
remains the only commercial source for the narcotic analgesics morphine, codeine and semi …
remains the only commercial source for the narcotic analgesics morphine, codeine and semi …
[PDF][PDF] Medicinal natural products: A biosynthetic approach
PM Dewick - 2002 - just.edu.jo
Medicinal Natural Products, Second Edition is a comprehensive guide providing information
on all classes of natural products in medicine. It builds upon fundamental chemical …
on all classes of natural products in medicine. It builds upon fundamental chemical …
[HTML][HTML] Manipulating the biosynthesis of bioactive compound alkaloids for next-generation metabolic engineering in opium poppy using CRISPR-Cas 9 genome …
Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated9
(Cas9) endonuclease system is a powerful RNA-guided genome editing tool. CRISPR/Cas9 …
(Cas9) endonuclease system is a powerful RNA-guided genome editing tool. CRISPR/Cas9 …
The chemical diversity of bioactive molecules and therapeutic potential of medicinal plants
KG Ramawat, S Dass, M Mathur - Herbal drugs: ethnomedicine to modern …, 2009 - Springer
The therapeutic use of herbs is as old as human civilization and has evolved along with it.
The vast majority of people on this planet still rely on their indigenous system of medicine …
The vast majority of people on this planet still rely on their indigenous system of medicine …
Anticancer and reversing multidrug resistance activities of natural isoquinoline alkaloids and their structure-activity relationship
ZX Qing, JL Huang, XY Yang, JH Liu… - Current medicinal …, 2018 - ingentaconnect.com
The severe anticancer situation as well as the emergence of multidrug-resistant (MDR)
cancer cells has created an urgent need for the development of novel anticancer drugs with …
cancer cells has created an urgent need for the development of novel anticancer drugs with …
Isoquinoline alkaloids and their antiviral, antibacterial, and antifungal activities and structure-activity relationship
ZX Qing, P Yang, Q Tang, P Cheng… - Current Organic …, 2017 - ingentaconnect.com
Background & Objective: The emergence of multidrug-resistant virus, bacteria and fungi has
created an urgent need for the development of novel antibiotic drugs from natural products …
created an urgent need for the development of novel antibiotic drugs from natural products …
Noscapine comes of age
X Chen, TTT Dang, PJ Facchini - Phytochemistry, 2015 - Elsevier
Noscapine is a phthalideisoquinoline alkaloid, which represents a class of plant specialized
metabolites within the large and structurally diverse group of benzylisoquinoline alkaloids …
metabolites within the large and structurally diverse group of benzylisoquinoline alkaloids …
DARK classics in chemical neuroscience: Morphine
AL Devereaux, SL Mercer… - ACS chemical …, 2018 - ACS Publications
As the major psychoactive agent in opium and direct precursor for heroin, morphine is a
historically critical molecule in chemical neuroscience. A structurally complex phenanthrene …
historically critical molecule in chemical neuroscience. A structurally complex phenanthrene …
Chromosome-level genome assembly of Aristolochia contorta provides insights into the biosynthesis of benzylisoquinoline alkaloids and aristolochic acids
X Cui, F Meng, X Pan, X Qiu, S Zhang, C Li… - Horticulture …, 2022 - academic.oup.com
Aristolochic acids (AAs) and their derivatives are present in multiple Aristolochiaceae
species that have been or are being used as medicinal materials. During the past decades …
species that have been or are being used as medicinal materials. During the past decades …