Deciphering the Structural Diversity and Classification of the Mobile Tigecycline Resistance Gene tet(X)-Bearing Plasmidome among Bacteria

R Li, X Lu, K Peng, Z Liu, Y Li, Y Liu, X Xiao, Z Wang - Msystems, 2020 - Am Soc Microbiol
The emergence of novel plasmid-mediated resistance genes constitutes a great public
concern. Recently, mobile tet (X) variants were reported in diverse pathogens from different …

Characterization of TMexCD3-TOprJ3, an RND-type efflux system conferring resistance to tigecycline in Proteus mirabilis, and its associated integrative conjugative …

Q Wang, K Peng, Y Liu, X Xiao, Z Wang… - Antimicrobial Agents …, 2021 - Am Soc Microbiol
The emergence and transmission of novel antimicrobial resistance genes pose a great
threat to public health globally. Recently, the plasmid-encoding RND efflux pump TMexCD1 …

Plasmids Shape the Current Prevalence of tmexCD1-toprJ1 among Klebsiella pneumoniae in Food Production Chains

K Peng, Q Wang, Y Yin, Y Li, Y Liu, M Wang, SS Qin… - Msystems, 2021 - Am Soc Microbiol
The emergence of novel antimicrobial resistance genes conferring resistance to last-resort
antimicrobials poses a serious challenge to global public health security. Recently, one …

Applying rapid whole-genome sequencing to predict phenotypic antimicrobial susceptibility testing results among carbapenem-resistant Klebsiella pneumoniae …

PD Tamma, Y Fan, Y Bergman, G Pertea… - Antimicrobial agents …, 2019 - Am Soc Microbiol
Standard antimicrobial susceptibility testing (AST) approaches lead to delays in the
selection of optimal antimicrobial therapy. Here, we sought to determine the accuracy of …

Tracking of antibiotic resistance transfer and rapid plasmid evolution in a hospital setting by Nanopore sequencing

S Peter, M Bosio, C Gross, D Bezdan, J Gutierrez… - Msphere, 2020 - Am Soc Microbiol
Infections with multidrug-resistant bacteria often leave limited or no treatment options. The
transfer of antimicrobial resistance genes (ARG) carrying plasmids between bacterial …

Coexistence of tet(X4), mcr-1, and blaNDM-5 in ST6775 Escherichia coli Isolates of Animal Origin in China

X Lu, Y Du, K Peng, W Zhang, J Li, Z Wang… - Microbiology …, 2022 - Am Soc Microbiol
Emergence of pathogens harboring multiple resistance genes incurs great concerns.
Cooccurrence of mobile resistance genes conferring resistance to tigecycline, colistin, and …

Whole‐Genome Sequence of Synthesized Allopolyploids in Cucumis Reveals Insights into the Genome Evolution of Allopolyploidization

X Yu, P Wang, J Li, Q Zhao, C Ji, Z Zhu… - Advanced …, 2021 - Wiley Online Library
The importance of allopolyploidy in plant evolution has been widely recognized. The genetic
changes triggered by allopolyploidy, however, are not yet fully understood due to …

Heterogeneous and Flexible Transmission of mcr-1 in Hospital-Associated Escherichia coli

Y Shen, Z Wu, Y Wang, R Zhang, HW Zhou, S Wang… - MBio, 2018 - Am Soc Microbiol
The recent emergence of a transferable colistin resistance mechanism, MCR-1, has gained
global attention because of its threat to clinical treatment of infections caused by multidrug …

[HTML][HTML] Identification of pathogens in culture-negative infective endocarditis cases by metagenomic analysis

J Cheng, H Hu, Y Kang, W Chen, W Fang… - Annals of clinical …, 2018 - Springer
Background Pathogens identification is critical for the proper diagnosis and precise
treatment of infective endocarditis (IE). Although blood and valve cultures are the gold …

Widespread Prevalence of Plasmid-Mediated Colistin Resistance Gene mcr-1 in Escherichia coli from Père David's Deer in China

X Lu, X Xiao, Y Liu, S Huang, R Li, Z Wang - Msphere, 2020 - Am Soc Microbiol
ABSTRACT Père David's deer (Elaphurus davidianus or milu) is an endangered species,
and the prevalence of antimicrobial resistance (AMR) such as mcr-1-positive strains among …