COVID-19 vaccine development: milestones, lessons and prospects

M Li, H Wang, L Tian, Z Pang, Q Yang… - Signal transduction and …, 2022 - nature.com
With the constantly mutating of SARS-CoV-2 and the emergence of Variants of Concern
(VOC), the implementation of vaccination is critically important. Existing SARS-CoV-2 …

Comparing COVID-19 vaccines for their characteristics, efficacy and effectiveness against SARS-CoV-2 and variants of concern: a narrative review

T Fiolet, Y Kherabi, CJ MacDonald, J Ghosn… - Clinical Microbiology …, 2022 - Elsevier
Background Vaccines are critical cost-effective tools to control the coronavirus disease 2019
(COVID-19) pandemic. However, the emergence of variants of the severe acute respiratory …

Duration of protection against mild and severe disease by Covid-19 vaccines

N Andrews, E Tessier, J Stowe, C Gower… - … England Journal of …, 2022 - Mass Medical Soc
Background Vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2), the virus that causes coronavirus disease 2019 (Covid-19), have been used since …

Efficacy of covid-19 vaccines in immunocompromised patients: systematic review and meta-analysis

ARYB Lee, SY Wong, LYA Chai, SC Lee, MX Lee… - Bmj, 2022 - bmj.com
Objective To compare the efficacy of covid-19 vaccines between immunocompromised and
immunocompetent people. Design Systematic review and meta-analysis. Data sources …

Effectiveness and safety of SARS-CoV-2 vaccine in real-world studies: a systematic review and meta-analysis

Q Liu, C Qin, M Liu, J Liu - Infectious diseases of poverty, 2021 - mednexus.org
Background: To date, coronavirus disease 2019 (COVID-19) becomes increasingly fierce
due to the emergence of variants. Rapid herd immunity through vaccination is needed to …

COVID-19 vaccines in patients with cancer: immunogenicity, efficacy and safety

A Fendler, EGE de Vries… - Nature Reviews …, 2022 - nature.com
Patients with cancer have a higher risk of severe coronavirus disease (COVID-19) and
associated mortality than the general population. Owing to this increased risk, patients with …

The SARS-CoV-2 monoclonal antibody combination, AZD7442, is protective in nonhuman primates and has an extended half-life in humans

YM Loo, PM McTamney, RH Arends… - Science translational …, 2022 - science.org
Despite the success of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
vaccines, there remains a need for more prevention and treatment options for individuals …

A COVID-19 peptide vaccine for the induction of SARS-CoV-2 T cell immunity

JS Heitmann, T Bilich, C Tandler, A Nelde, Y Maringer… - Nature, 2022 - nature.com
T cell immunity is central for the control of viral infections. CoVac-1 is a peptide-based
vaccine candidate, composed of SARS-CoV-2 T cell epitopes derived from various viral …

Immune responses to two and three doses of the BNT162b2 mRNA vaccine in adults with solid tumors

RT Shroff, P Chalasani, R Wei, D Pennington… - Nature medicine, 2021 - nature.com
Vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have
shown high efficacy, but immunocompromised participants were excluded from controlled …

CD8+ T cells contribute to survival in patients with COVID-19 and hematologic cancer

EM Bange, NA Han, P Wileyto, JY Kim, S Gouma… - Nature medicine, 2021 - nature.com
Patients with cancer have high mortality from coronavirus disease 2019 (COVID-19), and the
immune parameters that dictate clinical outcomes remain unknown. In a cohort of 100 …