Fibrin, a natural hydrogel, is the end product of the physiological blood coagulation cascade
and naturally involved in wound healing. Beyond its role in hemostasis, it acts as a local …

Regenerative medicine aims to create functional tissue replacements, typically through
creating a controlled environment that promotes and directs the differentiation of stem or …

Gene delivery has been extensively investigated for introducing foreign genetic material into
cells to promote expression of therapeutic proteins or to silence relevant genes. This …

Although viral gene transfer is efficient in achieving transgene expression for tissue
engineering, drawbacks of virus dissemination, toxicity and transient gene expression due to …

Fibrin is a natural biopolymer involved in the coagulation cascade. It acts as a reservoir for
growth factors, cells, and enzymes during wound healing and provides a scaffold for the …

Integrating viral gene delivery with engineered biomaterials is a promising strategy to
overcome a number of challenges associated with virus-mediated gene delivery, including …

Simple Summary Oncolytic virotherapy (OVT) is a promising approach in cancer
immunotherapy. Oncolytic viruses (OVs) could be applied in cancer immunotherapy without …

In the last decade, both regenerative medicine and nanotechnology have been broadly
developed leading important advances in biomedical research as well as in clinical practice …

Delivery of bioactive factors is a very valuable strategy for articular cartilage repair.
Nevertheless, the direct supply of such biomolecules is limited by several factors including …

In this study, we examined the use of polyethyleneimine (PEI) as a carrier for gene delivery
in human adipose tissue-derived stem cells (hADSCs). These multipotent cells can form …