rtdsm—An open‐source software for radiotherapy dose‐surface map generation and analysis
HM Patrick, J Kildea - Medical physics, 2022 - Wiley Online Library
Background Dose‐outcome studies in radiation oncology have historically excluded spatial
information due to dose‐volume histograms being the most dominant source of dosimetric …
information due to dose‐volume histograms being the most dominant source of dosimetric …
Estimating the percentage of patients who might benefit from proton beam therapy instead of X-ray radiotherapy
Objectives: High-energy Proton Beam Therapy (PBT) commenced in England in 2018 and
NHS England commissions PBT for 1.5% of patients receiving radical radiotherapy. We …
NHS England commissions PBT for 1.5% of patients receiving radical radiotherapy. We …
Predicting cancer relapse following lung stereotactic radiotherapy: an external validation study using real-world evidence
Purpose For patients receiving lung stereotactic ablative radiotherapy (SABR), evidence
suggests that high peritumor density predicts an increased risk of microscopic disease …
suggests that high peritumor density predicts an increased risk of microscopic disease …
Experimental validation of a novel method of dose accumulation for the rectum
HM Patrick, E Poon, J Kildea - Acta Oncologica, 2023 - Taylor & Francis
Abstract Background Dose-surface maps (DSMs) are an increasingly popular tool to
evaluate spatial dose-outcome relationships for the rectum. Recently, DSM addition has …
evaluate spatial dose-outcome relationships for the rectum. Recently, DSM addition has …
[HTML][HTML] Dose-volume analysis of planned versus accumulated dose as a predictor for late gastrointestinal toxicity in men receiving radiotherapy for high-risk prostate …
Background and purpose Significant dose deviations have been reported between planned
(DP) and accumulated (DA) dose in prostate radiotherapy. This study aimed to develop …
(DP) and accumulated (DA) dose in prostate radiotherapy. This study aimed to develop …
More than one way to skin a dose volume: the impact of dose-surface map calculation approach on study reproducibility
HM Patrick, J Kildea - Physics in Medicine & Biology, 2024 - iopscience.iop.org
Objective. Dose-surface maps (DSMs) provide spatial representations of the radiation dose
to organ surfaces during radiotherapy and are a valuable tool for identifying dose deposition …
to organ surfaces during radiotherapy and are a valuable tool for identifying dose deposition …
[HTML][HTML] Impact of radiation dose distribution on nutritional supplementation needs in head and neck cancer radiotherapy: a voxel-based machine learning approach
S Madhavan, M Gamez, YI Garces, SC Lester… - Frontiers in …, 2024 - frontiersin.org
Objectives To investigate the relationship between nutritional supplementation and radiation
dose to the pharyngeal constrictor muscles and larynx for head and neck (HN) cancer …
dose to the pharyngeal constrictor muscles and larynx for head and neck (HN) cancer …
[HTML][HTML] Predictors for late genitourinary toxicity in men receiving radiotherapy for high-risk prostate cancer using planned and accumulated dose
Background and purpose Significant deviations between bladder dose planned (DP) and
dose accumulated (DA) have been reported in patients receiving radiotherapy for prostate …
dose accumulated (DA) have been reported in patients receiving radiotherapy for prostate …
[HTML][HTML] Machine-learning with region-level radiomic and dosimetric features for predicting radiotherapy-induced rectal toxicities in prostate cancer patients
Z Yang, DJ Noble, L Shelley, T Berger, R Jena… - Radiotherapy and …, 2023 - Elsevier
Background and purpose This study aims to build machine learning models to predict
radiation-induced rectal toxicities for three clinical endpoints and explore whether the …
radiation-induced rectal toxicities for three clinical endpoints and explore whether the …
radial data mining to identify density–dose interactions that predict distant failure following SABR
Purpose Lower dose outside the planned treatment area in lung stereotactic radiotherapy
has been linked to increased risk of distant metastasis (DM) possibly due to underdosage of …
has been linked to increased risk of distant metastasis (DM) possibly due to underdosage of …