Purine and purinergic receptors
G Burnstock - Brain and neuroscience advances, 2018 - journals.sagepub.com
Adenosine 5′-triphosphate acts as an extracellular signalling molecule (purinergic
signalling), as well as an intracellular energy source. Adenosine 5′-triphosphate receptors …
signalling), as well as an intracellular energy source. Adenosine 5′-triphosphate receptors …
International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapy
MP Abbracchio, G Burnstock, JM Boeynaems… - Pharmacological …, 2006 - ASPET
There have been many advances in our knowledge about different aspects of P2Y receptor
signaling since the last review published by our International Union of Pharmacology …
signaling since the last review published by our International Union of Pharmacology …
Pharmacology and structure of P2Y receptors
I von Kügelgen, K Hoffmann - Neuropharmacology, 2016 - Elsevier
Abstract P2Y receptors are G-protein-coupled receptors (GPCRs) for extracellular
nucleotides. There are eight mammalian P2Y receptor subtypes (P2Y 1, P2Y 2, P2Y 4, P2Y …
nucleotides. There are eight mammalian P2Y receptor subtypes (P2Y 1, P2Y 2, P2Y 4, P2Y …
Cellular distribution and functions of P2 receptor subtypes in different systems
G Burnstock, GE Knight - Int Rev Cytol, 2004 - books.google.com
In 1929 Drury and Szent-Györgyi published a seminal paper describing the potent actions of
adenine compounds. Some decades later, adenosine 5'-triphosphate (ATP) was proposed …
adenine compounds. Some decades later, adenosine 5'-triphosphate (ATP) was proposed …
Coupling of P2Y receptors to G proteins and other signaling pathways
L Erb, GA Weisman - Wiley Interdisciplinary Reviews …, 2012 - Wiley Online Library
Abstract P2Y receptors are G protein‐coupled receptors (GPCRs) that are activated by
adenine and uridine nucleotides and nucleotide sugars. There are eight subtypes of P2Y …
adenine and uridine nucleotides and nucleotide sugars. There are eight subtypes of P2Y …
Mutant G-protein-coupled receptors as a cause of human diseases
T Schöneberg, A Schulz, H Biebermann… - Pharmacology & …, 2004 - Elsevier
G-protein-coupled receptors (GPCR) are involved in directly and indirectly controlling an
extraordinary variety of physiological functions. Their key roles in cellular communication …
extraordinary variety of physiological functions. Their key roles in cellular communication …
Molecular pharmacology of P2Y receptor subtypes
I von Kuegelgen - Biochemical Pharmacology, 2021 - Elsevier
Abstract Professor Geoffrey Burnstock proposed the concept of purinergic signaling via P1
and P2 receptors. P2Y receptors are G-protein-coupled receptors (GPCRs) for extracellular …
and P2 receptors. P2Y receptors are G-protein-coupled receptors (GPCRs) for extracellular …
Pharmacology of P2Y receptors
I von Kügelgen - Brain research bulletin, 2019 - Elsevier
Abstract P2Y receptors are G-protein-coupled receptors (GPCRs) for extracellular
nucleotides. There are eight mammalian P2Y receptor subtypes divided into two subgroups …
nucleotides. There are eight mammalian P2Y receptor subtypes divided into two subgroups …
P2Y nucleotide receptors: promise of therapeutic applications
KA Jacobson, JM Boeynaems - Drug discovery today, 2010 - Elsevier
Extracellular nucleotides, such as ATP and UTP, have distinct signaling roles through a
class of G-protein-coupled receptors, termed P2Y. The receptor ligands are typically …
class of G-protein-coupled receptors, termed P2Y. The receptor ligands are typically …
Purinergic neuron-to-glia signaling in the enteric nervous system
BD Gulbransen, KA Sharkey - Gastroenterology, 2009 - Elsevier
BACKGROUND & AIMS: Enteric glia are intimately associated with neurons in the enteric
nervous system (ENS) and display morphologic and molecular similarities to central nervous …
nervous system (ENS) and display morphologic and molecular similarities to central nervous …