The genus Diaporthe: a rich source of diverse and bioactive metabolites

C Chepkirui, M Stadler - Mycological Progress, 2017 - Springer
The genus Diaporthe (asexual state: Phomopsis) comprises pathogenic, endophytic and
saprobic species with both temperate and tropical distributions. Although species of …

Garlic-derived natural polysulfanes as hydrogen sulfide donors: Friend or foe?

E Yagdi, C Cerella, M Dicato, M Diederich - Food and Chemical Toxicology, 2016 - Elsevier
In vitro and in vivo studies reported the anti-cancer potential of organosulfur compounds
(OSCs) as they trigger biological effects leading to cell cycle arrest with accumulation of cells …

Smart nanocarrier based on PEGylated hyaluronic acid for deacetyl mycoepoxydience: High stability with enhanced bioavailability and efficiency

J Zhao, Y Wang, Y Ma, Y Liu, B Yan, L Wang - Carbohydrate polymers, 2019 - Elsevier
Deacetyl mycoepoxydience (DM) nanocrystals core were stabilized by the folate modified
distearoylphosphatidyl ethanolamine-polyethylene glycol (DSPE-PEG 2000-FA) as the …

The novel agent ophiobolin O induces apoptosis and cell cycle arrest of MCF-7 cells through activation of MAPK signaling pathways

T Yang, Z Lu, L Meng, S Wei, K Hong, W Zhu… - Bioorganic & medicinal …, 2012 - Elsevier
Ophiobolin O is a natural compound that has been isolated from Aspergillus ustus 094102.
This is the first study to demonstrate the anti-proliferative effect of ophiobolin O in human …

Secondary Metabolites Isolated from the Amazonian Endophytic Fungus Diaporthe sp. SNB-GSS10

H Mandavid, AMS Rodrigues… - Journal of natural …, 2015 - ACS Publications
We describe a Sabicea cinerea endophytic fungus closely related to Diaporthe
pseudomangiferae that produces two known metabolites, mycoepoxydiene (1) and altiloxin …

Vaccinols J–S, ten new salicyloid derivatives from the marine mangrove-derived endophytic fungus Pestalotiopsis vaccinii

JF Wang, R Liang, SR Liao, B Yang, ZC Tu, XP Lin… - Fitoterapia, 2017 - Elsevier
Ten new salicyloid derivatives, namely vaccinols J–S (1− 10), along with five known
compounds (11–15) were isolated from Pestalotiopsis vaccinii (cgmcc3. 9199) endogenous …

Current research landscape of marine-derived anti-atherosclerotic substances

Q Cao, J Zhao, M Xing, H Xiao, Q Zhang, H Liang, A Ji… - Marine drugs, 2020 - mdpi.com
Atherosclerosis is a chronic disease characterized by lipid accumulation and chronic
inflammation of the arterial wall, which is the pathological basis for coronary heart disease …

Bioactive natural compounds from the mangrove endophytic fungi

KW Wang, SW Wang, B Wu… - Mini reviews in medicinal …, 2014 - ingentaconnect.com
In recent years, mangrove endophytic fungi are increasingly attracting attention of the
pharmaceutical community as they produce a wide variety of metabolites that are structurally …

Bioactive microbial metabolites in cancer therapeutics: mining, repurposing, and their molecular targets

S Pattnaik, M Imchen, R Kumavath, R Prasad… - Current microbiology, 2022 - Springer
The persistence and resurgence of cancer, characterized by abnormal cell growth and
differentiation, continues to be a serious public health concern critically affecting public …

Potential of endophytic Diaporthe sp. as a new source of bioactive compounds

K Nagarajan, WY Tong, CR Leong… - Journal of Microbiology …, 2020 - pmc.ncbi.nlm.nih.gov
Endophytic fungi are symbiotically related to plants and spend most of their life cycle within
them. In nature, they have a crucial role in plant micro-ecosystem. They are harnessed for …