Background Noninvasive and accurate modality to predict isocitrate dehydrogenase (IDH)
mutant glioma may have great potential in routine clinical practice. We aimed to investigate …

Objectives To evaluate the imaging features of isocitrate dehydrogenase (IDH) mutant
glioma and to assess the diagnostic performance of magnetic resonance imaging (MRI) for …

Background. High-grade gliomas with mutations in the isocitrate dehydrogenase (IDH) gene
family confer longer overall survival relative to their IDH-wild-type counterparts. Accurate …

Objective The status of isocitrate dehydrogenase 1 (IDH1) is highly correlated with the
development, treatment and prognosis of glioma. We explored a noninvasive method to …

Inhibitors of the mutant isocitrate dehydrogenase 1 (IDH1) entered recently in clinical trials
for glioma treatment. Mutant IDH1 produces high levels of 2-hydroxyglurate (2HG), thought …

Purpose To assess the amide proton transfer‐weighted (APTw) MRI features of isocitrate
dehydrogenase (IDH)‐wildtype and IDH‐mutant grade II gliomas and to test the hypothesis …

BACKGROUND AND PURPOSE: Isocitrate dehydrogenase (IDH) has been shown to have
both diagnostic and prognostic implications in gliomas. The purpose of this study was to …

Gliomas possess complex and heterogeneous vasculatures with abnormal hemodynamics.
Despite considerable advances in diagnostic and therapeutic techniques for improving …

BACKGROUND AND PURPOSE: Glioblastoma multiforme is highly aggressive and the most
common type of primary malignant brain tumor in adults. Imaging biomarkers may provide …

Purpose Reliable and accurate predictive models are necessary to drive the success of
radiomics. Our aim was to identify the optimal radiomics-based machine learning method for …