The potential of in vitro neuronal networks cultured on micro electrode arrays for biomedical research

M Cerina, MC Piastra, M Frega - Progress in Biomedical …, 2023 - iopscience.iop.org
In vitro neuronal models have become an important tool to study healthy and diseased
neuronal circuits. The growing interest of neuroscientists to explore the dynamics of …

Designing a bidirectional, adaptive neural interface incorporating machine learning capabilities and memristor-enhanced hardware

S Shchanikov, A Zuev, I Bordanov, S Danilin… - Chaos, solitons & …, 2021 - Elsevier
Building bidirectional biointerfaces is one of the key challenges of modern engineering and
medicine, with dramatic potential impact on bioprosthetics. Two of the major challenges of …

Use of multi-electrode array recordings in studies of network synaptic plasticity in both time and space

MG Liu, XF Chen, T He, Z Li, J Chen - Neuroscience bulletin, 2012 - Springer
Simultaneous multisite recording using multi-electrode arrays (MEAs) in cultured and
acutely-dissociated brain slices and other tissues is an emerging technique in the field of …

Design of Cultured Neuron Networks in vitro with Predefined Connectivity Using Asymmetric Microfluidic Channels

A Gladkov, Y Pigareva, D Kutyina, V Kolpakov… - Scientific reports, 2017 - nature.com
The architecture of neuron connectivity in brain networks is one of the basic mechanisms by
which to organize and sustain a particular function of the brain circuitry. There are areas of …

Information encoding in bursting spiking neural network modulated by astrocytes

SV Stasenko, VB Kazantsev - Entropy, 2023 - mdpi.com
We investigated a mathematical model composed of a spiking neural network (SNN)
interacting with astrocytes. We analysed how information content in the form of two …

Seizure-like activity in hyaluronidase-treated dissociated hippocampal cultures

M Vedunova, T Sakharnova, E Mitroshina… - Frontiers in cellular …, 2013 - frontiersin.org
The extracellular matrix (ECM) plays an important role in use-dependent synaptic plasticity.
Hyaluronic acid (HA) is the backbone of the neural ECM, which has been shown to …

A comparison of computational methods for detecting bursts in neuronal spike trains and their application to human stem cell-derived neuronal networks

E Cotterill, P Charlesworth… - Journal of …, 2016 - journals.physiology.org
Accurate identification of bursting activity is an essential element in the characterization of
neuronal network activity. Despite this, no one technique for identifying bursts in spike trains …

Parameters for burst detection

DJ Bakkum, M Radivojevic, U Frey, F Franke… - Frontiers in …, 2014 - frontiersin.org
Bursts of action potentials within neurons and throughout networks are believed to serve
roles in how neurons handle and store information, both in vivo and in vitro. Accurate …

High-throughput PEDOT: PSS/PtNPs-modified microelectrode array for simultaneous recording and stimulation of hippocampal neuronal networks in gradual learning …

S Xu, Y Deng, J Luo, E He, Y Liu, K Zhang… - … Applied Materials & …, 2022 - ACS Publications
When it comes to mechanisms of brain functions such as learning and memory mediated by
neural networks, existing multichannel electrophysiological detection and regulation …

Carbon nanotube multi-electrode array chips for noninvasive real-time measurement of dopamine, action potentials, and postsynaptic potentials

I Suzuki, M Fukuda, K Shirakawa, H Jiko… - Biosensors and …, 2013 - Elsevier
Multi-electrode arrays (MEAs) can be used for noninvasive, real-time, and long-term
recording of electrophysiological activity and changes in the extracellular chemical …